Related BioAssays, by Target Similarity (List) for PubChem BioAssay (S - PubChem BioAssay - NCBI

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Select item 19542381.

Inhibition of human SGLT2

Source:: ChEMBL

Protein Target:: Sodium/glucose cotransporter 2

Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1954238

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19434652.

Inhibition of human SGLT1

Source:: ChEMBL

Protein Target:: Sodium/glucose cotransporter 1

Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested

AID:: 1943465

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19434643.

Inhibition of human SGLT2

Source:: ChEMBL

Protein Target:: Sodium/glucose cotransporter 2

Assay data:3 Active, 1 Activity ≤ 1 nM, 3 Activity ≤ 1 µM, 3 Tested

AID:: 1943464

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19242274.

Inhibition of SGLT1 (unknown origin)

Source:: ChEMBL

Protein Target:: Sodium/glucose cotransporter 1

Assay data:1 Active, 1 Tested

AID:: 1924227

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 19242265.

Inhibition of SGLT2 (unknown origin)

Source:: ChEMBL

Protein Target:: Sodium/glucose cotransporter 2

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1924226

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 18884906.

Inhibition of human SGLT1 expressed in CHO cells by methyl-alpha-D-glucopyranoside assay

Source:: ChEMBL

Protein Target:: Sodium/glucose cotransporter 1

Assay data:14 Active, 9 Activity ≤ 1 µM, 14 Tested

AID:: 1888490

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 18884897.

Inhibition of human SGLT2 expressed in CHO cells by methyl-alpha-D-glucopyranoside assay

Source:: ChEMBL

Protein Target:: Sodium/glucose cotransporter 2

Assay data:20 Active, 9 Activity ≤ 1 nM, 20 Activity ≤ 1 µM, 20 Tested

AID:: 1888489

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 18744418.

Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C] labeled AMG accumulation incubated for 15 mins

Source:: ChEMBL

Protein Target:: Sodium/glucose cotransporter 2

Assay data:6 Active, 6 Activity ≤ 1 µM, 6 Tested

AID:: 1874441

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 18744409.

Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of [14C] labeled AMG accumulation incubated for 15 mins

Source:: ChEMBL

Protein Target:: Sodium/glucose cotransporter 1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1874440

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 187443810.

Inhibition of recombinant human SGLT2 expressed in COS-7 cells assessed as inhibition of [14C]AMG uptake

Source:: ChEMBL

Protein Target:: Sodium/glucose cotransporter 2

Assay data:1 Tested

AID:: 1874438

Summary PubMed Citation Related BioAssays by Target

Select item 187443711.

Inhibition of recombinant human SGLT1 expressed in COS-7 cells assessed as inhibition of [14C]AMG uptake

Source:: ChEMBL

Protein Target:: Sodium/glucose cotransporter 1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1874437

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 187443312.

Inhibition of full length N-terminal HA-tagged human SGLT2 expressed in HEK293 cells assessed as inhibition of [14C]AMG uptake

Source:: ChEMBL

Protein Target:: Sodium/glucose cotransporter 2

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1874433

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 187443213.

Inhibition of full length N-terminal HA-tagged human SGLT1 expressed in HEK293 cells assessed as inhibition of [14C]AMG uptake

Source:: ChEMBL

Protein Target:: Sodium/glucose cotransporter 1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1874432

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 187443014.

Inhibition of human SGLT2

Source:: ChEMBL

Protein Target:: Sodium/glucose cotransporter 2

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1874430

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 187442915.

Inhibition of human SGLT1

Source:: ChEMBL

Protein Target:: Sodium/glucose cotransporter 1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1874429

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 187442816.

Inhibition of human SGLT2 expressed in HEK293T cells using [14C] alpha-MDG as substrate incubated for 30 mins by scintillation counter method

Source:: ChEMBL

Protein Target:: Sodium/glucose cotransporter 2

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1874428

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 187442717.

Inhibition of human SGLT2 expressed in HEK293 cell membrane assessed as inhibition of [14C]AMG uptake

Source:: ChEMBL

Protein Target:: Sodium/glucose cotransporter 2

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1874427

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 187442618.

Inhibition of human SGLT1 expressed in HEK293 cell membrane assessed as inhibition of [14C]AMG uptake

Source:: ChEMBL

Protein Target:: Sodium/glucose cotransporter 1

Assay data:1 Active, 1 Tested

AID:: 1874426

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 187442319.

Inhibition of human SGLT2 expressed in COS-7 cells

Source:: ChEMBL

Protein Target:: Sodium/glucose cotransporter 2

Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested

AID:: 1874423

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 187442220.

Inhibition of human SGLT1 expressed in COS-7 cells

Source:: ChEMBL

Protein Target:: Sodium/glucose cotransporter 1

Assay data:2 Tested

AID:: 1874422

Summary PubMed Citation Related BioAssays by Target

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Target

Proteins (9)
BioAssays with protein sequences specified as targets

BioActivity

Active Compounds (217)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (39)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (188)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Confirmatory (208)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations

Depositor Category

Literature Extraction (267)
BioAssays extracted from the literature
Other (1)
BioAssays deposited by other experimentalists

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Chromosome neighbors for GEO Profiles (Select 131978490) (19)
GEO Profiles
Chromosome neighbors for GEO Profiles (Select 131980715) (16)
GEO Profiles
Taxonomy Links for Nucleotide (Select 82350859) (1)
Taxonomy
SYN2 synapsin II [Homo sapiens]
SYN2 synapsin II [Homo sapiens]
Gene ID:6854

Gene

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