Related BioAssays, by Target Similarity (List) for PubChem BioAssay (S - PubChem BioAssay - NCBI

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Select item 19542381.

Inhibition of human SGLT2

Source:: ChEMBL

Protein Target:: Sodium/glucose cotransporter 2

Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1954238

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19434652.

Inhibition of human SGLT1

Source:: ChEMBL

Protein Target:: Sodium/glucose cotransporter 1

Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested

AID:: 1943465

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19434643.

Inhibition of human SGLT2

Source:: ChEMBL

Protein Target:: Sodium/glucose cotransporter 2

Assay data:3 Active, 1 Activity ≤ 1 nM, 3 Activity ≤ 1 µM, 3 Tested

AID:: 1943464

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19242274.

Inhibition of SGLT1 (unknown origin)

Source:: ChEMBL

Protein Target:: Sodium/glucose cotransporter 1

Assay data:1 Active, 1 Tested

AID:: 1924227

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 19242265.

Inhibition of SGLT2 (unknown origin)

Source:: ChEMBL

Protein Target:: Sodium/glucose cotransporter 2

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1924226

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 18884906.

Inhibition of human SGLT1 expressed in CHO cells by methyl-alpha-D-glucopyranoside assay

Source:: ChEMBL

Protein Target:: Sodium/glucose cotransporter 1

Assay data:14 Active, 9 Activity ≤ 1 µM, 14 Tested

AID:: 1888490

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 18884897.

Inhibition of human SGLT2 expressed in CHO cells by methyl-alpha-D-glucopyranoside assay

Source:: ChEMBL

Protein Target:: Sodium/glucose cotransporter 2

Assay data:20 Active, 9 Activity ≤ 1 nM, 20 Activity ≤ 1 µM, 20 Tested

AID:: 1888489

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 18744418.

Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C] labeled AMG accumulation incubated for 15 mins

Source:: ChEMBL

Protein Target:: Sodium/glucose cotransporter 2

Assay data:6 Active, 6 Activity ≤ 1 µM, 6 Tested

AID:: 1874441

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 18744409.

Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of [14C] labeled AMG accumulation incubated for 15 mins

Source:: ChEMBL

Protein Target:: Sodium/glucose cotransporter 1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1874440

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 187443810.

Inhibition of recombinant human SGLT2 expressed in COS-7 cells assessed as inhibition of [14C]AMG uptake

Source:: ChEMBL

Protein Target:: Sodium/glucose cotransporter 2

Assay data:1 Tested

AID:: 1874438

Summary PubMed Citation Related BioAssays by Target

Select item 187443711.

Inhibition of recombinant human SGLT1 expressed in COS-7 cells assessed as inhibition of [14C]AMG uptake

Source:: ChEMBL

Protein Target:: Sodium/glucose cotransporter 1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1874437

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 187443312.

Inhibition of full length N-terminal HA-tagged human SGLT2 expressed in HEK293 cells assessed as inhibition of [14C]AMG uptake

Source:: ChEMBL

Protein Target:: Sodium/glucose cotransporter 2

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1874433

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 187443213.

Inhibition of full length N-terminal HA-tagged human SGLT1 expressed in HEK293 cells assessed as inhibition of [14C]AMG uptake

Source:: ChEMBL

Protein Target:: Sodium/glucose cotransporter 1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1874432

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 187443014.

Inhibition of human SGLT2

Source:: ChEMBL

Protein Target:: Sodium/glucose cotransporter 2

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1874430

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 187442915.

Inhibition of human SGLT1

Source:: ChEMBL

Protein Target:: Sodium/glucose cotransporter 1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1874429

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 187442816.

Inhibition of human SGLT2 expressed in HEK293T cells using [14C] alpha-MDG as substrate incubated for 30 mins by scintillation counter method

Source:: ChEMBL

Protein Target:: Sodium/glucose cotransporter 2

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1874428

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 187442717.

Inhibition of human SGLT2 expressed in HEK293 cell membrane assessed as inhibition of [14C]AMG uptake

Source:: ChEMBL

Protein Target:: Sodium/glucose cotransporter 2

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1874427

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 187442618.

Inhibition of human SGLT1 expressed in HEK293 cell membrane assessed as inhibition of [14C]AMG uptake

Source:: ChEMBL

Protein Target:: Sodium/glucose cotransporter 1

Assay data:1 Active, 1 Tested

AID:: 1874426

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 187442319.

Inhibition of human SGLT2 expressed in COS-7 cells

Source:: ChEMBL

Protein Target:: Sodium/glucose cotransporter 2

Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested

AID:: 1874423

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 187442220.

Inhibition of human SGLT1 expressed in COS-7 cells

Source:: ChEMBL

Protein Target:: Sodium/glucose cotransporter 1

Assay data:2 Tested

AID:: 1874422

Summary PubMed Citation Related BioAssays by Target

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Target

Proteins (9)
BioAssays with protein sequences specified as targets

BioActivity

Active Compounds (217)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (39)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (188)
BioAssays with the active concentration of tested reagents less than 1 micromolar

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Confirmatory (208)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations

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Literature Extraction (267)
BioAssays extracted from the literature
Other (1)
BioAssays deposited by other experimentalists

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