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Inhibition of LOX and LOXL1-4 from US Patent US20230349907: "BIOPROBES FOR LYSYL OXIDASES AND USES THEREOF"
Assay data:10 Active, 16 Activity ≤ 1 µM, 16 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Human LOXL2 Purified Recombinant Protein Assay from US Patent US11793797: "Uses of a lysyl oxidase-like 2 inhibitor"
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
Human LOX CCM Assay from US Patent US11793797: "Uses of a lysyl oxidase-like 2 inhibitor"
LOXL2 AmineOxidase Activity Assay from US Patent US11793797: "Uses of a lysyl oxidase-like 2 inhibitor"
Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested
Monoamine Oxidase A (MAO-A) Selectivity Assay from US Patent US11608330: "Methylamine derivatives as lysysl oxidase inhibitors for the treatment of cancer"
Assay data:42 Active, 40 Activity ≤ 1 µM, 42 Tested
LOXL2 Enzyme Activity Assay (20 min) from US Patent US11608330: "Methylamine derivatives as lysysl oxidase inhibitors for the treatment of cancer"
Assay data:16 Active, 1 Activity ≤ 1 µM, 18 Tested
Inhibition of recombinant human LOXL-2
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Human LOXL2 CCM Assay from US Patent US11459309: "Crystalline forms of a lysyl oxidase-like 2 inhibitor and methods of making"
Human LOXL2 Amine Oxidase Activity Assay from US Patent US11358936: "Lysyl oxidase-like 2 inhibitors and uses thereof"
Assay data:96 Active, 102 Activity ≤ 1 µM, 102 Tested
Amine Oxidase Activity Assay from US Patent US11345676: "Apoptosis signal-regulating kinase 1 (ASK 1) inhibitor compounds"
Assay data:3 Active, 4 Activity ≤ 1 µM, 4 Tested
Inhibition Assay from US Patent US11098045: "Haloallylamine indole and azaindole derivative inhibitors of lysyl oxidases and uses thereof"
Assay data:116 Active, 116 Activity ≤ 1 µM, 116 Tested
Human LOXL2 Amine Oxidase Activity Assay from US Patent US11058676: "Quinolinone lysyl oxidase-like 2 inhibitors and uses thereof"
Assay data:20 Active, 21 Activity ≤ 1 µM, 21 Tested
Amine Oxidase Activity Assay from US Patent US11072585: "Fluorinated lysyl oxidase-like 2 inhibitors and uses thereof"
Assay data:111 Active, 115 Activity ≤ 1 µM, 115 Tested
LOXL2 Enzyme Activity Assay (i hour) from US Patent US10995088: "Methylamine derivatives as lysysl oxidase inhibitors for the treatment of cancer"
Assay data:46 Active, 38 Activity ≤ 1 µM, 47 Tested
LOXL2 Enzyme Activity Assay (20 hours) from US Patent US10995088: "Methylamine derivatives as lysysl oxidase inhibitors for the treatment of cancer"
LOXL2 Enzyme Activity Assay (20 minutes) from US Patent US10995088: "Methylamine derivatives as lysysl oxidase inhibitors for the treatment of cancer"
LOXL2 Enzyme Activity Assay (b) from US Patent US10807974: "Methylamine derivatives as lysysl oxidase inhibitors for the treatment of cancer"
LOXL2 Enzyme Activity Assay (c) from US Patent US10807974: "Methylamine derivatives as lysysl oxidase inhibitors for the treatment of cancer"
Assay data:41 Active, 39 Activity ≤ 1 µM, 41 Tested
LOXL2 Enzyme Activity Assay (a) from US Patent US10807974: "Methylamine derivatives as lysysl oxidase inhibitors for the treatment of cancer"
Assay data:15 Active, 1 Activity ≤ 1 µM, 17 Tested
Human LOXL2 CCM Assay from US Patent US10774069: "Crystalline forms of a lysyl oxidase-like 2 inhibitor and methods of making"
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