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thallium-flux assay from US Patent US11632953: "Method for controlling hematophagous or sap-feeding arthropods"
Assay data:7 Active, 9 Tested
SummaryCompounds, ActiveRelated BioAssays by Target
Inhibition of human Kir2.1 expressed in Xenopus laevis oocytes assessed as inhibition of channel current at 10 uM at +40mV holding potential by two-electrode voltage clamp assay
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of recombinant human Kir2.1 expressed in human HEK293 cells at 100 uM measured at end current by automated Qpatch clamp assay relative to control
Inhibition of recombinant human Kir2.1 expressed in human HEK293 cells at 30 uM measured at end current by automated Qpatch clamp assay relative to control
Inhibition of recombinant human Kir2.1 expressed in human HEK293 cells at 3 uM measured at end current by automated Qpatch clamp assay relative to control
Inhibition of recombinant human Kir2.1 expressed in human HEK293 cells at 100 uM measured at peak current by automated Qpatch clamp assay relative to control
Inhibition of recombinant human Kir2.1 expressed in human HEK293 cells at 30 uM measured at peak current by automated Qpatch clamp assay relative to control
Inhibition of recombinant human Kir2.1 expressed in human HEK293 cells at 3 uM measured at peak current by automated Qpatch clamp assay relative to control
Inhibition of human Kir2.1
Activation of Kir2.1 (unknown origin) at 30 uM by manual patch clamp method relative to control
Inhibition of Kir2.3 (unknown origin) upto 30 uM
Inhibition of Kir2.1 (unknown origin) upto 30 uM
Inhibition of human Kir2.1 expressed in HEK293 cells at 10 uM by manual patch clamp assay
Assay data:4 Tested
Inhibition of Kir2.1 (unknown origin) at 3 uM relative to control
Activity at human Kir2.1 at 10 uM
Inhibition of Kir2.1 (unknown origin) at 30 uM
Inhibition of Kir2.1 (unknown origin)
Inhibition of Kir2.1 (unknown origin) by patch clamp assay
Inhibition of human Kir2.1 expressed in CHO cells by automated patch clamp assay
Inhibition of human Kir2.1 at 10 uM by patch clamp method relative to control
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