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Inhibition of VISTA (unknown origin) incubated for 15 mins by LANCE Ultra TR-FRET assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Binding affinity to recombinant human His-tagged VISTA extracellular binding domain incubated for 30 mins by microscale thermophoresis analysis
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Binding affinity to recombinant human VISTA ECD incubated for 2 hrs by ELISA assay
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Binding affinity to recombinant human His-tagged VISTA ECD incubated for 2 hrs by TR-FRET assay
Binding affinity to VISTA (unknown origin) assessed as dissociation constant
Inhibition of recombinant VISTA signalling pathway (unknown origin) at 10 uM by HTRF assay relative to control
Binding affinity to VISTA (unknown origin) assessed as dissociation constant by MST method
Assay data:1 Active, 1 Activity ≤ 1 µM, 2 Tested
Inhibition of VISTA (unknown origin)
Inhibition of VISTA (unknown origin) by ELISA method
Inhibition of VISTA in human PBMC
Inhibition of VISTA signaling in human PBMC assessed as IFNgamma release at 100 nM after 30 mins by ELISA
Assay data:2 Tested
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