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Inhibition of Maxi-K (unknown origin) expressed in HEK293 cells at 30 uM measured by thallium flux assay relative to control
Assay data:2 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of Maxi-K (unknown origin) expressed in HEK293 cells measured by thallium flux assay
Assay data:4 Tested
Activation of rat Slo expressed in Xenopus laevis oocytes assessed as delayed channel closing 10 uM with 100 mV holding potential by patch-clamp electrophysiological method
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Activation of rat Slo expressed in Xenopus laevis oocytes assessed as shortened channel opening 10 uM with 100 mV holding potential by patch-clamp electrophysiological method
Activation of rat Slo expressed in Xenopus laevis oocytes assessed as increase in intracellular maximum conductance at 10 uM with 100 mV holding potential by patch-clamp electrophysiological method relative to control
Assay data:1 Tested
Activation of rat Slo expressed in Xenopus laevis oocytes assessed as intracellular shift in voltage at half activation at 10 uM with 100 mV holding potential by patch-clamp electrophysiological method
Activation of rat Slo expressed in Xenopus laevis oocytes assessed as increase in maximum conductance at 10 uM with 100 mV holding potential by patch-clamp electrophysiological method relative to control
Activation of rat Slo expressed in Xenopus laevis oocytes assessed as shift in voltage at half activation at 10 uM with 100 mV holding potential by patch-clamp electrophysiological method
Activation of rat Slo expressed in Xenopus laevis oocytes at 10 uM with 100 mV holding potential by patch-clamp electrophysiological method
Activation of human BKca expressed in HEK293T cells at 10 uM by patch clamp electrophysiology method
Activation of Maxi-K channel (unknown origin) by thallium flux assay
Agonist activity at rat BK calcium channel alpha expressed in CHO cells assessed as increase in current amplitude at 0.001 to 100 uM in presence of compound 3 by automated whole cell patch clamp analysis
Antagonist activity at rat BK calcium channel alpha expressed in CHO cells assessed as decrease in current amplitude at 10 uM by automated whole cell patch clamp analysis
Agonist activity at rat BK calcium channel alpha expressed in CHO cells assessed as fold change in current amplitude at 10 uM by automated whole cell patch clamp analysis
Agonist activity at rat BK calcium channel alpha expressed in CHO cells assessed as increase in current amplitude at 10 uM by automated whole cell patch clamp analysis
Inhibition of human BK potassium channel expressed in Xenopus laevis oocytes assessed as inhibition of channel current at 10 uM at +40mV holding potential by two-electrode voltage clamp assay
Potentiation of human KCa1.1 expressed in HEK293 cells at 100 uM with -90 mV holding potential measured at 1 to 2 days by patch clamp electrophysiology
SK+Ca channel CEREP ligand profiling
SummaryRelated BioAssays by Target
SKCa channel CEREP ligand profiling
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