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Glutamate, NMDA, Glycine Eurofins Panlabs panel
Assay data:1 Tested
SummaryRelated BioAssays by Target
Glutamate, NMDA, Agonism Eurofins Panlabs panel
NMDA/R Eurofins SafetyScreen44 (BI)
Antagonist activity at NMDA receptor (unknown origin) assessed as inhibition constant
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Positive allosteric modulator activity at NMDA receptor in rat Hippocampal neurone
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Positive allosteric modulation of GluN1/GluN2A receptor (unknown origin) stably expressed in HEK293 cells assessed as ratio of Fmax/F0 fluorescence curve value
Assay data:2 Tested
SummaryPubMed CitationRelated BioAssays by Target
Positive allosteric modulation of GluN1/GluN2A receptor (unknown origin) stably expressed in HEK293 cells assessed as glutamate/glycine induced increase in intracellular calcium level at 10 uM incubated for 30 mins followed by addition of glutamate/glycine by Ca2+ influx assay
Assay data:4 Active, 4 Tested
Displacement of [3H]ifenprodyl from NMDA receptor (unknown origin)
Displacement of [3H]MDL from NMDA receptor (unknown origin)
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
Positive allosteric modulator activity at GluN2A NMDA receptor (unknown origin) expressed in CHO cells co-expressing GluN1a assessed as maximum potentiation at 30 uM in the presence of L-glutamate and glycine by Ca2+ influx assay relative to control
Assay data:18 Tested
Positive allosteric modulator activity at GluN2A NMDA receptor (unknown origin) expressed in CHO cells co-expressing GluN1a in the presence of L-glutamate and glycine by Ca2+ influx assay
Assay data:10 Active, 3 Activity ≤ 1 µM, 18 Tested
Blocking of NMDA receptor in mouse fibroblast assessed as inhibition of NMDA-induced excitotoxicity by LDH release assay
Inhibition of NMDA receptor (unknown origin) at 10 uM
NR2B Radioligand Binding Assay from US Patent US11752155: "Treatment of autism spectrum disorders, obsessive-compulsive disorder and anxiety disorders"
Assay data:11 Tested
SummaryRelated BioAssays by DepositorRelated BioAssays by Target
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