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Inhibition of human liver FBPase expressed in Escherichia coli BL21 (DE3) measured after 48 hrs by spectrophotometry analysis
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of recombinant C-terminal His-tagged human liver FBPase expressed in Escherichia coli BL21 (DE3)
Assay data:5 Active, 1 Activity ≤ 1 µM, 5 Tested
Inhibition of human liver FBPase expressed in Escherichia coli
Assay data:2 Active, 2 Activity ≤ 1 µM, 4 Tested
Inhibition of human liver FBPase expressed in Escherichia coli by spectrophotometry method
Assay data:1 Active, 1 Activity ≤ 1 µM, 3 Tested
Inhibition of human liver FBPase
Assay data:7 Active, 5 Activity ≤ 1 µM, 8 Tested
Inhibition of human liver FBPase by spectrophotometric method
Assay data:10 Active, 7 Activity ≤ 1 µM, 13 Tested
Inhibition of FBPase in rat Primary hepatocyte assessed as reduction in glucose production
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of FBPase in rat Primary hepatocyte assessed as reduction in glucose production at 160 uM
Inhibition of FBPase (unknown origin)
Assay data:4 Active, 4 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of human FBPase in ICR mouse serum starved primary hepatocytes assessed as glucose lowering effect at 50 to 100 uM
Inhibition of human FBPase in ICR mouse serum starved primary hepatocytes assessed as glucose lowering effect
Assay data:1 Active, 1 Tested
Binding affinity to ABPP-labeled FBPase (unknown origin) at 2 to 8 uM by silver staining based streptavidin blotting
Binding affinity to ABPP-labeled FBPase (unknown origin) by silver staining based streptavidin blotting
Inhibition of human FBPase expressed Escherichia coli BL21 in by malachite green dye based spectrophotometry
Assay data:7 Active, 9 Tested
Spectrophotometrical Assay from US Patent US9273021: "Dibenzofuran derivatives as inhibitors of fructose 1,6-bisphosphatase and methods of use thereof"
Assay data:2 Active, 3 Tested
SummaryCompounds, ActiveRelated BioAssays by Target
Inhibition of human FBPase Y258A mutant
Inhibition of human FBPase R243A mutant
Inhibition of human FBPase D127A mutant
Inhibition of human FBPase N125A mutant
Inhibition of human FBPase S124A mutant
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