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Cross screening panel
Assay data:1 Tested
SummaryRelated BioAssays by Target
Safety47 Scan (DiscoverX - Eurofins)
Calcium Channel L-Type, Dihydropyridine Eurofins Panlabs panel
Calcium Channel L-Type, Benzothiazepine Eurofins Panlabs panel
CA+/DHPSI/R Eurofins SafetyScreen44 (BI)
Compound was evaluated for inhibition of human CACNA1C in an in vitro cell-based assay measured by IonWorks automated patch clamp
Assay data:14 Active, 3 Activity ≤ 1 µM, 116 Tested
Compound was evaluated for inhibition of rat Cacna1c in an in vitro assay with cellular components measured by membrane filtration
Assay data:31 Active, 1 Activity ≤ 1 nM, 14 Activity ≤ 1 µM, 943 Tested
Inhibition of Cav1.2 channel (unknown origin) upto 10000 nM
Displacement of [3H]D 888 from rat brain L-type calcium channel verapamil binding site at 10 uM after 120 mins by scintillation counting analysis relative to control
Assay data:3 Tested
Inhibition of Cav1.2 (unknown origin) at 10 uM
Inhibition of recombinant human Cav1.2
Assay data:4 Tested
Inhibition of Cav1.2 (unknown origin) at 50 uM relative to control
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