Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Antagonist activity against human integrin alphaVbeta3 expressed in CHO-K1 cells measured after 4 hrs by Cell adhesion assay
Assay data:3 Active, 3 Activity ≤ 1 nM, 3 Activity ≤ 1 µM, 3 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Solid Phase Integrin αvβ1 Binding Assay from US Patent US20230365556: "N-ACYL AMINO ACID COMPOUNDS AND METHODS OF USE"
Assay data:20 Active, 23 Activity ≤ 1 µM, 23 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Solid Phase Integrin alphaVbeta6 Binding Assay from US Patent US20230293519: "INTEGRIN INHIBITORS AND USES THEREOF IN COMBINATION WITH OTHER AGENTS"
Assay data:118 Active, 137 Activity ≤ 1 µM, 137 Tested
Inhibition of Integrin-Ligand Interaction by Reference Inhibitors from US Patent US11685738: "Fluorinated tetrahydronaphthyridinyl nonanoic acid derivatives and uses thereof"
Assay data:14 Active, 1 Activity ≤ 1 nM, 14 Activity ≤ 1 µM, 14 Tested
Solid Phase Integrin alphavbeta6 Binding Assay from US Patent US11634418: "Amino acid compounds and methods of use"
Assay data:137 Active, 154 Activity ≤ 1 µM, 155 Tested
Solid Phase Integrin alphavbeta6 Binding Assay from US Patent US11560376: "Amino acid compounds and methods of use"
Assay data:125 Active, 145 Activity ≤ 1 µM, 145 Tested
Solid Phase Integrin alphaVbeta6 Binding Assay from US Patent US20230271960: "AMINO ACID COMPOUNDS AND METHODS OF USE"
Assay data:124 Active, 144 Activity ≤ 1 µM, 144 Tested
Inhibition of human recombinant integrin alphavbeta3 incubated for 1 hr by ELISA assay
Assay data:1 Active, 8 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of human recombinant integrin alphavbeta6 incubated for 1 hr by ELISA assay
Assay data:2 Active, 8 Tested
Antagonist activity at human alphaVbeta3 Integrin assessed as inhibition constant
Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of recombinant human alphavbeta6 integrin incubated for 2 hrs by microplate reader assay
Assay data:6 Active, 6 Activity ≤ 1 µM, 6 Tested
Inhibition of alpha2bbeta3 integrin receptor expressed on human surface of platelets
Assay data:3 Activity ≤ 1 µM, 3 Tested
SummaryCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of alphavbeta5 integrin receptor-mediated cell adhesion to vitronectin in human HT-29 cells
Assay data:1 Active, 1 Activity ≤ 1 µM, 4 Tested
Inhibition of alphavbeta3 integrin receptor-mediated cell adhesion to fibrinogen in human HEK293 cells
Assay data:4 Active, 2 Activity ≤ 1 µM, 4 Tested
Inhibition of alphavbeta3 integrin receptor-mediated cell adhesion to fibrinogen in human SK-OV-3 cells expressing alphavbeta5 integrin receptor
Inhibition of alphavbeta3 integrin receptor-mediated cell adhesion to vitronectin in human A549 cells preincubated for 30 mins followed by VN substrate addition and measured after 1 hr by crystal violet based staining method
Assay data:1 Active, 1 Activity ≤ 1 µM, 3 Tested
Inhibition of alphavbeta3 integrin receptor-mediated cell adhesion to vitronectin in human WM 266-4 cells preincubated for 30 mins followed by VN substrate addition and measured after 1 hr by crystal violet based staining method
Assay data:3 Active, 1 Activity ≤ 1 µM, 3 Tested
Solid Phase Integrin alphav/beta6 Binding Assay (B-2) from US Patent US11419869: "Dosage forms and regimens for amino acid compounds"
Assay data:35 Active, 40 Activity ≤ 1 µM, 40 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
Solid Phase Integrin alphav/beta6 Binding Assay (B-1) from US Patent US11419869: "Dosage forms and regimens for amino acid compounds"
Assay data:90 Active, 105 Activity ≤ 1 µM, 105 Tested
Solid Phase Integrin αVβ6 Binding Assay from US Patent US11396506: "Amino acid compounds with unbranched linkers and methods of use"
Assay data:15 Active, 15 Activity ≤ 1 µM, 15 Tested
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on