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Inhibition of TDO (unknown origin) expressed in HEK cells
Assay data:6 Tested
SummaryPubMed CitationRelated BioAssays by Target
TDO2 Enzymatic Inhibition Assay from US Patent US11572354: "Inhibitor of indoleamine 2,3-dioxygenase-1 and methods of manufacture and use thereof"
Assay data:8 Tested
SummaryRelated BioAssays by DepositorRelated BioAssays by Target
Inhibition of TDO (unknown origin)
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of TDO in human A-172 cells
Inhibition of human TDO by UV based assay
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of TDO in human BT-549 cells
Assay data:1 Active, 1 Activity ≤ 1 µM, 3 Tested
Inhibition of recombinant C-terminal His tagged TDO (unknown origin) expressed in Escherichia coli
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
Assay data:6 Active, 3 Activity ≤ 1 µM, 7 Tested
Inhibition of TDO in overexpressing human A-172 cells
Assay data:2 Active, 3 Tested
Inhibition of TDO in overexpressing human SW48 cells
Inhibition of human TDO (19 to 388 aa) expressed in Escherichia coli Transetta (DE3) by nanodrop 2000c spectrophotometric analysis
Assay data:26 Active, 14 Activity ≤ 1 µM, 44 Tested
Binding affinity to human TDO assessed as inhibition constant by Cornhish-Bowden method
Inhibition of human TDO by Cornhish-Bowden method
Assay data:2 Active, 2 Tested
Inhibition of human TDO
Assay data:3 Active, 3 Activity ≤ 1 µM, 6 Tested
Competitive inhibition of recombinant human TDO measured by UV/visible spectrophotometric method
Competitive inhibition of recombinant human TDO measured by surface plasmon resonance assay
Inhibition of TDO in human HEK293 cells assessed as reduction in kynurenine formation using L-tryptophan as substrate by absorbance based analysis
Assay data:12 Active, 4 Activity ≤ 1 µM, 21 Tested
Inhibition of recombinant human TDO assessed as reduction in N-formylkynurenine formation using L-tryptophan as substrate and measured after 15 mins
Assay data:20 Active, 11 Activity ≤ 1 µM, 32 Tested
Inhibition of human TDO2 expressed in mouse P815B cells using L-tryptophan as substrate incubated for 7 hrs by UPLC analysis
Assay data:5 Active, 5 Activity ≤ 1 µM, 5 Tested
Inhibition of human TDO2 expressed in Escherichia coli BL21-DE3 rosetta cells at pH 6.5 potassium phosphate buffer using L-tryptophan as substrate measured after 15 mins
Assay data:5 Active, 5 Tested
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