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ITK Invitrogen Lab (UK) kinase screen (BI)
Assay data:1 Tested
SummaryRelated BioAssays by Target
Inhibition of ITK (unknown origin) at 1 uM relative to control
Inhibition of ITK (unknown origin) by Z'LYTE assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 2 Tested
Inhibition of ITK (unknown origin) using Blk/Lyntide as substrate preincubated for 1 hr followed by substrate addition and measured after 2 hrs in presence of ATP by IMAP assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of ITK (unknown origin) by Ambit kinase assay
Inhibition of ITK (unknown origin)
Assay data:2 Activity ≤ 1 µM, 2 Tested
Inhibition of human ITK at 1 uM by hotspot assay relative to control
ITK Enzyme Assay from US Patent US20230280220: "Benzimidazole Derivative Compounds and Uses Thereof"
Assay data:54 Active, 2 Activity ≤ 1 nM, 54 Activity ≤ 1 µM, 54 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
ITK Enzyme Assay from US Patent US11661419: "Benzimidazole derivative compounds and uses thereof"
Selectivity interaction (33P-ATP and filter-binding assay (Reaction Biology)) EUB0000646a ITK
Selectivity interaction ( p-PLCg1 assay) EUB0000646a ITK
Assay data:1 Active, 1 Tested
SummaryCompounds, ActiveRelated BioAssays by Target
Selectivity interaction (Z?-LYTE assay) EUB0000638a ITK
Inhibition of ITK (unknown origin) at 0.3 uM relative to control
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of human ITK assessed as residual activity at 30 uM relative to control
Inhibition of ITK (unknown origin) by lanthascreen Tb kinase activity assay
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
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