Related BioAssays, by Target Similarity (List) for PubChem BioAssay (S - PubChem BioAssay - NCBI

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Select item 19629091.

new record, indexing in progress

AID:: 1962909

Select item 19628052.

new record, indexing in progress

AID:: 1962805

Select item 19627713.

new record, indexing in progress

AID:: 1962771

Select item 19626724.

new record, indexing in progress

AID:: 1962672

Select item 19498225.

new record, indexing in progress

AID:: 1949822

Select item 19339826.

new record, indexing in progress

AID:: 1933982

Select item 19241567.

new record, indexing in progress

AID:: 1924156

Select item 19202188.

TTK Enzyme Assay from US Patent US11884671: "Purinone compounds and their use in treating cancer"

Source:: BindingDB

Protein Targets:: Dual specificity protein kinase TTK; ...
Total:: 1

Assay data:46 Active, 22 Activity ≤ 1 µM, 51 Tested

AID:: 1920218

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Depositor Related BioAssays by Target

Select item 19141229.

Selectivity interaction (SelectScreen (Invitrogen)) EUB0000715a TTK

Source:: ChEMBL

Protein Target:: Dual specificity protein kinase TTK

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1914122

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 191407810.

Selectivity interaction (KinomeScan (DiscoverX)) EUB0000138c TTK

Source:: ChEMBL

Protein Target:: Dual specificity protein kinase TTK

Assay data:1 Tested

AID:: 1914078

Summary Related BioAssays by Target

Select item 191381711.

Selectivity interaction (KinomeScan (DiscoverX)) EUB0000691a TTK

Source:: ChEMBL

Protein Target:: Dual specificity protein kinase TTK

Assay data:1 Tested

AID:: 1913817

Summary Related BioAssays by Target

Select item 191309812.

Affinity Biochemical interaction (LanthaScreen Eu kinase binding assay) EUB0000642a TTK

Source:: ChEMBL

Protein Target:: Dual specificity protein kinase TTK

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1913098

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 191308713.

Affinity Biochemical interaction (TR-FRET-based in vitro kinase assays) EUB0000634a TTK

Source:: ChEMBL

Protein Target:: Dual specificity protein kinase TTK

Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1913087

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 191306214.

Affinity Biochemical interaction (Ambit Competition binding assay) EUB0000609a TTK

Source:: ChEMBL

Protein Target:: Dual specificity protein kinase TTK

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1913062

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 191306115.

Affinity Biochemical interaction (Ambit Competition binding assay) EUB0000608a TTK

Source:: ChEMBL

Protein Target:: Dual specificity protein kinase TTK

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1913061

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 191268516.

Affinity Phenotypic Cellular interaction (Western Blot (phosphorylation of TTK T686 in Cal-51 cells)) EUB0000642a TTK

Source:: ChEMBL

Protein Target:: Dual specificity protein kinase TTK

Assay data:1 Tested

AID:: 1912685

Summary Related BioAssays by Target

Select item 191267417.

Affinity Phenotypic Cellular interaction (Mps1 kinase phosphorylation assay (abolished KNL1 Thr-875 phosphorylation in A2780 cells pretreated with 100 nmol/L paclitaxel)) EUB0000634a TTK

Source:: ChEMBL

Protein Target:: Dual specificity protein kinase TTK

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1912674

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 191265418.

Affinity Phenotypic Cellular interaction (Immunoblot activity assay (using LAP-Mps1 WT in U2OS cells)) EUB0000609a TTK

Source:: ChEMBL

Protein Target:: Dual specificity protein kinase TTK

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1912654

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 191265319.

Affinity Phenotypic Cellular interaction (Immunoblot activity assay (using LAP-Mps1 WT in U2OS cells)) EUB0000608a TTK

Source:: ChEMBL

Protein Target:: Dual specificity protein kinase TTK

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1912653

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 191260720.

Thermal Shift Assay. Domain: start/stop: S519-E808

Source:: ChEMBL

Protein Target:: Dual specificity protein kinase TTK

Assay data:27 Tested

AID:: 1912607

Summary Related BioAssays by Target

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Proteins (3)
BioAssays with protein sequences specified as targets

BioActivity

Active Compounds (136)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (42)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (121)
BioAssays with the active concentration of tested reagents less than 1 micromolar

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Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations

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Literature Extraction (270)
BioAssays extracted from the literature
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BioAssays deposited by the NIH Molecular Libraries Program
Other (32)
BioAssays deposited by other experimentalists

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