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Inhibition of human milk xanthine oxidase relative to control
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of XOD (unknown origin) using xanthine as substrate assessed as inhibition of uric acid generation at 0.54 mg/L preincubated for 15 mins followed by xanthine addition and measured by spectrophotometric analysis relative to control
Inhibition of XOD (unknown origin) using xanthine as substrate assessed as inhibition of uric acid generation at 150 mg/L preincubated for 15 mins followed by xanthine addition and measured by spectrophotometric analysis relative to control
Inhibition of XOD (unknown origin) using xanthine as substrate assessed as inhibition of uric acid generation at 100 mg/L preincubated for 15 mins followed by xanthine addition and measured by spectrophotometric analysis relative to control
Inhibition of XOD (unknown origin) using xanthine as substrate assessed as inhibition of uric acid generation at 50 mg/L preincubated for 15 mins followed by xanthine addition and measured by spectrophotometric analysis relative to control
Mixed-type inhibition of xanthine oxidase (unknown origin) assessed as decrease in Vmax with increasing Km at 0.02 to 0.06 uM by Lineweaver-Burk plot analysis
Assay data:3 Active, 3 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Mixed-type inhibition of xanthine oxidase (unknown origin) assessed as Inhibitor dissociation constant using xanthine as substrate incubated for 15 mins followed by substrate addition by UV spectrophotometric analysis
Assay data:5 Active, 1 Activity ≤ 1 nM, 5 Activity ≤ 1 µM, 5 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Competitive inhibition of xanthine oxidase (unknown origin) assessed as inhibitory constant of enzyme-substrate complex using xanthine as substrate at varying concentrations preincubated for 15 mins followed by substrate addition by UV spectrophotometric analysis
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Mixed-type inhibition of xanthine oxidase (unknown origin) assessed as inhibitory constant of enzyme-substrate complex using xanthine as substrate at varying concentrations preincubated for 15 mins followed by substrate addition by UV spectrophotometric analysis
Inhibition of xanthine oxidase (unknown origin) using xanthine as substrate preincubated for 15 mins followed by substrate addition by UV spectrophotometric analysis
Assay data:37 Active, 35 Activity ≤ 1 µM, 37 Tested
Inhibition of xanthine oxidase (unknown origin) at 0.1 uM measured by spectrophotometric analysis relative to control
Inhibition of xanthine oxidase (unknown origin) at 10 uM measured by spectrophotometric analysis relative to control
Assay data:20 Tested
Inhibition of xanthine oxidase (unknown origin) measured by spectrophotometric analysis
Assay data:7 Active, 6 Activity ≤ 1 µM, 7 Tested
Mixed-type inhibition of xanthine oxidase (unknown origin) assessed as decrease in Vmax with increasing Km up to 0.1 uM using varying concentrations of xanthine as substrate incubated for 15 mins followed by substrate addition by Lineweaver-Burk plot analysis
Assay data:1 Active, 1 Tested
Mixed-type inhibition of xanthine oxidase (unknown origin) assessed as decrease in Vmax with increasing Km up to 0.125 uM using varying concentrations of xanthine as substrate incubated for 15 mins followed by substrate addition by Lineweaver-Burk plot analysis
Inhibition of xanthine oxidase (unknown origin) using xanthine as substrate incubated for 15 mins followed by substrate addition by spectrophotometric analysis
Assay data:30 Active, 22 Activity ≤ 1 µM, 39 Tested
Inhibition of bovine XO assessed as inhibition of uric acid formation using xanthine as substrate at 25 uM preincubated with enzyme for 10 mins followed by substrate addition and measured for 2 mins by spectrophotometry
Assay data:10 Tested
Potency index, ratio of allopurinol IC50 to test compound IC50 for bovine XO using xanthine as substrate by spectrophotometry
Inhibition of bovine XO assessed as inhibition of uric acid formation using xanthine as substrate preincubated with enzyme for 10 mins followed by substrate addition and measured for 2 mins by spectrophotometry
Assay data:22 Active, 2 Activity ≤ 1 µM, 30 Tested
Mixed type inhibition of bovine XOD assessed as decrease in Vmax with increase in Km at upto 20 uM using varying levels of xanthine as substrate by Lineweaver-Burk plot analysis
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