Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
In Vitro Activity Assay from US Patent US11944616: "Dizocilpine derivatives as peripheral NMDA receptor antagonists"
Assay data:10 Active, 9 Activity ≤ 1 µM, 10 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Cross screening panel
Assay data:1 Tested
SummaryRelated BioAssays by Target
Safety47 Scan (DiscoverX - Eurofins)
Glutamate, NMDA, Glycine Eurofins Panlabs panel
Glutamate, NMDA, Agonism Eurofins Panlabs panel
NMDA/R Eurofins SafetyScreen44 (BI)
Binding affinity towards rat Grin1 in an in vitro assay with cellular components measured by membrane filtration
Assay data:10 Active, 4 Activity ≤ 1 µM, 1125 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Antagonist activity at NMDA receptor (unknown origin) assessed as inhibition constant
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of GluN1/GluN2B NMDA receptor (unknown origin) expressed in HEK293 cells
Assay data:2 Active, 1 Activity ≤ 1 µM, 5 Tested
Positive allosteric modulator activity at NMDA receptor in rat Hippocampal neurone
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Positive allosteric modulation of GluN1/GluN2B receptor (unknown origin) stably expressed in HEK293 cells assessed as glutamate/glycine induced increase in intracellular calcium level at 10 uM incubated for 30 mins followed by addition of glutamate/glycine by Ca2+ influx assay
Assay data:3 Active, 4 Tested
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on