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Panlabs assay PDE9A2
Assay data:1 Tested
SummaryRelated BioAssays by Target
3H-cAMP and 3H-cGMP Scintillation Proximity Assay (PDE9A)
Assay data:1 Active, 1 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Inhibition of PDE9A (unknown origin) by 3H-cAMP scintillation proximity assay
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of human PDE9A expressed in Escherichia coli DH10 by scintillation proximity assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of recombinant PDE9A (181 to 506 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H]-cGMP as substrate measured for 15 mins by liquid scintillation counter method
Assay data:4 Active, 2 Activity ≤ 1 µM, 4 Tested
Inhibition of PDE9 (unknown origin) using 3[H]-cGMP as substrate incubated for 15 mins by liquid scintillation counter
Inhibition of PDE9A (unknown origin)
Assay data:3 Active, 3 Activity ≤ 1 µM, 4 Tested
PDE9 Inhibition Assay from US Patent US11608342: "PDE9 inhibitors with imidazo triazinone backbone and imidazo pyrazinone backbone for treatment of peripheral diseases"
Assay data:5 Active, 5 Activity ≤ 1 µM, 5 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
Selectivity interaction (PDE panel (enzymatic activity assay)) EUB0000751a PDE9A
Selectivity interaction (PDE panel (enzymatic assay)) EUB0000744a PDE9A
Inhibition of PDE9A (181 to 506 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H]-cGMP as substrate at 10000 nM measured for 15 mins by liquid scintillation counter method
Inhibition of PDE9A2 (181 to 506 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H]-cGMP as substrate measured for 15 mins by liquid scintillation counter method
Inhibition of PDE9A2 (181 to 506 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H-GMP] or [3H-AMP] as substrate incubated for 15 mins by liquid scintillation counting method
Inhibition of rat PDE9A using [3H]-cGMP as substrate at 42 nM incubated for 60 mins by microbeta scintillation counter analysis relative to control
Inhibition of full length human PDE9A expressed in Sf9 insect cells using [3H]-cGMP as substrate incubated for 60 mins by microbeta scintillation counter analysis
Assay data:33 Active, 32 Activity ≤ 1 µM, 34 Tested
Inhibition of PDE9 in human SH-SY5Y cells measured after 2 hrs by Western blot analysis
Inhibition of PDE9A2 (unknown origin)
Inhibition of PDE9 (unknown origin)
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