Related BioAssays, by Target Similarity (List) for PubChem BioAssay (S - PubChem BioAssay - NCBI

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Select item 19479141.

Binding affinity to FPR2 (unknown origin) at 10 uM by radioligand binding assay

Source:: ChEMBL

Protein Target:: N-formyl peptide receptor 2

Assay data:1 Tested

AID:: 1947914

Summary PubMed Citation Related BioAssays by Target

Select item 19479132.

Binding affinity to FPR1 (unknown origin) at 10 uM by radioligand binding assay

Source:: ChEMBL

Protein Target:: fMet-Leu-Phe receptor

Assay data:1 Tested

AID:: 1947913

Summary PubMed Citation Related BioAssays by Target

Select item 19322393.

Agonist activity at human FPR2 expressed in CHO-K1 cells by beta-arrestin recruitment assay

Source:: ChEMBL

Protein Target:: N-formyl peptide receptor 2

Assay data:1 Active, 1 Tested

AID:: 1932239

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 19322384.

Agonist activity at mouse FPR3 expressed in CHO-A12 cells assessed as cAMP level incubated for 1.5 hr by HTRF assay

Source:: ChEMBL

Protein Target:: Formyl peptide receptor-related sequence 1

Assay data:1 Activity ≤ 1 µM, 1 Tested

AID:: 1932238

Summary Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19322375.

Agonist activity at human FPR2 expressed in CHO cells assessed as increase in calcium flux incubated for 50 mins by FLIPR calcium 5 dye based fluorescence assay

Source:: ChEMBL

Protein Target:: N-formyl peptide receptor 2

Assay data:7 Active, 7 Activity ≤ 1 nM, 7 Activity ≤ 1 µM, 7 Tested

AID:: 1932237

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19322366.

Agonist activity at human FPR1 expressed in CHO cells assessed as increase in calcium flux incubated for 50 mins by FLIPR calcium 5 dye based fluorescence assay

Source:: ChEMBL

Protein Target:: fMet-Leu-Phe receptor

Assay data:7 Active, 7 Activity ≤ 1 nM, 7 Activity ≤ 1 µM, 7 Tested

AID:: 1932236

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19322357.

Agonist activity at human FPR2 expressed in HEK293 cells assessed as increase in calcium flux incubated for 60 mins by FLIPR assay

Source:: ChEMBL

Protein Target:: N-formyl peptide receptor 2

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1932235

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19322268.

Agonist activity at mouse FPR2 expressed in CHO-A12 cells assessed as cAMP level incubated for 1.5 hr by HTRF assay

Source:: ChEMBL

Protein Target:: Formyl peptide receptor 2

Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested

AID:: 1932226

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19322259.

Agonist activity at mouse FPR1 expressed in CHO-A12 cells assessed as cAMP level incubated for 1.5 hr by HTRF assay

Source:: ChEMBL

Protein Target:: fMet-Leu-Phe receptor

Assay data:2 Active, 1 Activity ≤ 1 nM, 2 Activity ≤ 1 µM, 2 Tested

AID:: 1932225

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 193222410.

Agonist activity at human FPR2 expressed in CHO-A12 cells assessed as cAMP level incubated for 1.5 hr by HTRF assay

Source:: ChEMBL

Protein Target:: N-formyl peptide receptor 2

Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested

AID:: 1932224

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 193222311.

Agonist activity at human FPR1 expressed in CHO-A12 cells assessed as cAMP level incubated for 1.5 hr by HTRF assay

Source:: ChEMBL

Protein Target:: fMet-Leu-Phe receptor

Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested

AID:: 1932223

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 193221912.

Agonist activity at human FPR2 expressed in HEK293 cells assessed as increase in calcium flux incubated for 45 mins by Fluo-4 AM dye based fluorescence assay

Source:: ChEMBL

Protein Target:: N-formyl peptide receptor 2

Assay data:10 Active, 8 Activity ≤ 1 nM, 10 Activity ≤ 1 µM, 10 Tested

AID:: 1932219

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 193221813.

Agonist activity at FPR2 (unknown origin) assessed as increase in calcium flux

Source:: ChEMBL

Protein Target:: N-formyl peptide receptor 2

Assay data:4 Active, 3 Activity ≤ 1 nM, 4 Activity ≤ 1 µM, 4 Tested

AID:: 1932218

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 193221714.

Agonist activity at human FPR1 expressed in CHO cells assessed as cAMP level incubated for 1.5 hr by HTRF assay

Source:: ChEMBL

Protein Target:: fMet-Leu-Phe receptor

Assay data:17 Active, 7 Activity ≤ 1 µM, 30 Tested

AID:: 1932217

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 193221615.

Agonist activity at human FPR2 expressed in CHO cells assessed as cAMP level incubated for 1.5 hr by HTRF assay

Source:: ChEMBL

Protein Target:: N-formyl peptide receptor 2

Assay data:44 Active, 4 Activity ≤ 1 nM, 44 Activity ≤ 1 µM, 44 Tested

AID:: 1932216

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 193221416.

Agonist activity at human recombinant FPR2 stably transfected in Flp-In-CHO cells assessed as ERK1/2 phosphorylation at 10 uM incubated for 1 hr by Alphascreen fluorescence assay relative to control

Source:: ChEMBL

Protein Target:: N-formyl peptide receptor 2

Assay data:3 Tested

AID:: 1932214

Summary PubMed Citation Related BioAssays by Target

Select item 193221317.

Agonist activity at human recombinant FPR1 stably transfected in Flp-In-CHO cells assessed as ERK1/2 phosphorylation at 10 uM incubated for 1 hr by Alphascreen fluorescence assay relative to control

Source:: ChEMBL

Protein Target:: fMet-Leu-Phe receptor

Assay data:3 Tested

AID:: 1932213

Summary PubMed Citation Related BioAssays by Target

Select item 193221218.

Agonist activity at human recombinant FPR2 stably transfected in Flp-In-CHO cells assessed as ERK1/2 phosphorylation incubated for 1 hr by Alphascreen fluorescence assay

Source:: ChEMBL

Protein Target:: N-formyl peptide receptor 2

Assay data:2 Active, 3 Tested

AID:: 1932212

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 193221119.

Agonist activity at human recombinant FPR1 stably transfected in Flp-In-CHO cells assessed as ERK1/2 phosphorylation incubated for 1 hr by Alphascreen fluorescence assay

Source:: ChEMBL

Protein Target:: fMet-Leu-Phe receptor

Assay data:3 Active, 2 Activity ≤ 1 µM, 3 Tested

AID:: 1932211

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 193221020.

Agonist activity at human recombinant FPR2 stably transfected in Flp-In-CHO cells assessed as maximal intracellular calcium mobilization at 10 uM incubated for 1 hr by Fluo-4 AM dye based fluorescence plate reader assay relative to control

Source:: ChEMBL

Protein Target:: N-formyl peptide receptor 2

Assay data:3 Tested

AID:: 1932210

Summary PubMed Citation Related BioAssays by Target

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Target

Proteins (31)
BioAssays with protein sequences specified as targets

BioActivity

Chemical Probes (2)
BioAssays with compounds reported as validated chemical probes

Active Compounds (178)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (33)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (126)
BioAssays with the active concentration of tested reagents less than 1 micromolar

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Summary (2)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (151)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (10)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose

Assay Project (18)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

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Literature Extraction (273)
BioAssays extracted from the literature
NIH MLP (19)
BioAssays deposited by the NIH Molecular Libraries Program
Other (7)
BioAssays deposited by other experimentalists

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Related BioAssays, by Target Similarity (List) for PubChem BioAssay (Select 1932203)
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PubChem BioAssay
Compounds, Active for PubChem BioAssay (Select 1932237) (7)
PubChem Compound
cytochrome oxidase subunit 1, partial (mitochondrion) [Sarcoptiformes sp. BOLD:A...
cytochrome oxidase subunit 1, partial (mitochondrion) [Sarcoptiformes sp. BOLD:ACK8178]
gi|909747873|gb|AKT68442.1|

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