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Inhibition of PI3Kalpha (unknown origin) using PIP2:PS as substrate preincubated for 1 hr followed by ATP and substate addition and measured after 1 hr by ADP-glo reagent based assay
Assay data:22 Active, 2 Activity ≤ 1 µM, 48 Tested
SummaryRelated BioAssays by Target
Inhibition of PI3K-P85 phosphorylation in human HT-29 cells at 4 uM incubated for 72 hrs by Western blot analysis
Assay data:1 Active, 1 Tested
Inhibition of PI3K-P85 phosphorylation in human HT-29 cells at 2 uM incubated for 72 hrs by Western blot analysis
Inhibition of PI3K-P85 phosphorylation in human HT-29 cells at 1 uM incubated for 72 hrs by Western blot analysis
Inhibition of PI3Kalpha (unknown origin)
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
Inhibition of PI3K-p110alpha (unknown origin) incubated for 30 mins by fluorescence polarization assay
Inhibition of recombinant PI3K p110alpha/p85 (unknown origin) incubated for 1 hr in presence of gamma[33P]ATP by scintillation counting analysis
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of PI3Kalpha (unknown origin) preincubated for 10 mins followed by ATP addition and measured after 60 mins by ADP-Glo assay
Assay data:4 Active, 4 Activity ≤ 1 µM, 4 Tested
Binding affinity to PI3Kalpha (unknown origin) assessed as dissociation constant
Assay data:1 Tested
Inhibition of human P13Kalpha
Inhibition of PI3Kalpha in human MCF7 cells assessed as decrease in PI3Kalpha gene expression by measuring relative expression ratio at 0.8 uM incubated for 24 hrs by fluorescence quantitative PCR assay relative to control
Inhibition of PI3Kalpha in human MCF7 cells assessed as decrease in PI3Kalpha gene expression incubated for 24 hrs by fluorescence quantitative PCR assay
Inhibition of PI3Kalpha (unknown origin) by kinase-glo luminescent assay
Assay data:9 Active, 3 Activity ≤ 1 µM, 18 Tested
Inhibition of PI3Kalpha (unknown origin) at 1 uM by kinase-glo luminescent assay relative to control
Assay data:18 Tested
Inhibition of PI3 kinase p110alpha/p85alpha (unknown origin) at 1 uM relative to control
Inhibition of PI3 Kinase p110delta/p85alpha (unknown origin) at 1 uM relative to control
Inhibition of P13 kinase p110beta/p85alpha (unknown origin) at 1 uM relative to control
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