Related BioAssays, by Target Similarity (List) for PubChem BioAssay (S - PubChem BioAssay - NCBI

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Select item 19624421.

PTK2 Invitrogen Lab (UK) kinase screen (BI)

Source:: ChEMBL

Protein Target:: Focal adhesion kinase 1

Assay data:1 Tested

AID:: 1962442

Summary Related BioAssays by Target

Select item 19622952.

PTK2 Invitrogen Lab (UK) kinase screen (BI)

Source:: ChEMBL

Protein Target:: Focal adhesion kinase 1

Assay data:1 Tested

AID:: 1962295

Summary Related BioAssays by Target

Select item 19614703.

Inhibition of FAK (unknown origin)

Source:: ChEMBL

Protein Target:: Focal adhesion kinase 1

Assay data:3 Tested

AID:: 1961470

Summary PubMed Citation Related BioAssays by Target

Select item 19591584.

Inhibition of FAK (unknown origin) at 1000 nM by by DiscoverX KINOMEscan assay

Source:: ChEMBL

Protein Target:: Focal adhesion kinase 1

Assay data:1 Active, 1 Tested

AID:: 1959158

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 19559065.

Inhibition of FAK (unknown origin) at 1 uM relative to control

Source:: ChEMBL

Protein Target:: Focal adhesion kinase 1

Assay data:1 Tested

AID:: 1955906

Summary PubMed Citation Related BioAssays by Target

Select item 19498406.

Inhibition of FAK (unknown origin)

Source:: ChEMBL

Protein Target:: Focal adhesion kinase 1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1949840

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19408437.

Inhibition of FAK (unknown origin)

Source:: ChEMBL

Protein Target:: Focal adhesion kinase 1

Assay data:2 Activity ≤ 1 µM, 2 Tested

AID:: 1940843

Summary Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19368738.

Inhibition of FAK pathway in human A549/Taxol cells assessed as decrease in phosphorylated FAK level at 5 uM incubated for 24 hrs

Source:: ChEMBL

Protein Target:: Focal adhesion kinase 1

Assay data:1 Active, 1 Tested

AID:: 1936873

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 19368729.

Inhibition of FAK pathway in human A549/Taxol cells assessed as decrease in phosphorylated FAK level at 2.5 to 5 uM incubated for 24 hrs

Source:: ChEMBL

Protein Target:: Focal adhesion kinase 1

Assay data:1 Active, 1 Tested

AID:: 1936872

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 193463410.

Inhibition of FAK (unknown origin)

Source:: ChEMBL

Protein Target:: Focal adhesion kinase 1

Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested

AID:: 1934634

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 193463311.

Induction of degradation of Fak in human PC-3 cells assessed as maximum degradation relative to control

Source:: ChEMBL

Protein Target:: Focal adhesion kinase 1

Assay data:1 Tested

AID:: 1934633

Summary PubMed Citation Related BioAssays by Target

Select item 193463212.

Induction of degradation of Fak in human PC-3 cells

Source:: ChEMBL

Protein Target:: Focal adhesion kinase 1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1934632

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 191519813.

Selectivity interaction (KinomeScan (DiscoverX)) EUB0000545a PTK2

Source:: ChEMBL

Protein Target:: Focal adhesion kinase 1

Assay data:1 Tested

AID:: 1915198

Summary Related BioAssays by Target

Select item 191396114.

Selectivity interaction (KinomeScan (DiscoverX)) EUB0000702a PTK2

Source:: ChEMBL

Protein Target:: Focal adhesion kinase 1

Assay data:1 Tested

AID:: 1913961

Summary Related BioAssays by Target

Select item 191380615.

Selectivity interaction (Z?-LYTE assay (SelectScreen Invitrogen)) EUB0000690a PTK2

Source:: ChEMBL

Protein Target:: Focal adhesion kinase 1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1913806

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 191376316.

Selectivity interaction (Kinase panel (KiNativ method in HeLa cells)) EUB0000122b PTK2

Source:: ChEMBL

Protein Target:: Focal adhesion kinase 1

Assay data:1 Tested

AID:: 1913763

Summary Related BioAssays by Target

Select item 191341717.

Selectivity interaction (Enzymatic assay) EUB0000609a PTK2

Source:: ChEMBL

Protein Target:: Focal adhesion kinase 1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1913417

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 191317718.

Affinity Biochemical interaction (Binding assay) EUB0000138c PTK2

Source:: ChEMBL

Protein Target:: Focal adhesion kinase 1

Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1913177

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 191316519.

Affinity Biochemical interaction (Binding assay) EUB0000702a PTK2

Source:: ChEMBL

Protein Target:: Focal adhesion kinase 1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1913165

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 191292420.

Affinity On-target Cellular interaction (Inhibition of human PTK2 phosphorylation in A431 cells) EUB0000138c PTK2

Source:: ChEMBL

Protein Target:: Focal adhesion kinase 1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1912924

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

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Proteins (7)
BioAssays with protein sequences specified as targets

BioActivity

Active Compounds (293)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (27)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (167)
BioAssays with the active concentration of tested reagents less than 1 micromolar

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BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (253)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (1)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose

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BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

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Literature Extraction (719)
BioAssays extracted from the literature
NIH MLP (5)
BioAssays deposited by the NIH Molecular Libraries Program
Other (39)
BioAssays deposited by other experimentalists

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Related BioAssays, by Target Similarity (List) for PubChem BioAss... (763)
Related BioAssays, by Target Similarity (List) for PubChem BioAssay (Select 1949840)
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PubChem BioAssay
BioProject Links for Nucleotide (Select 1488063534) (1)
BioProject
PTK2 protein tyrosine kinase 2 [Homo sapiens]
PTK2 protein tyrosine kinase 2 [Homo sapiens]
Gene ID:5747

Gene
Gene Links for Protein (Select 1914782015) (1)
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