Related BioAssays, by Target Similarity (List) for PubChem BioAssay (S - PubChem BioAssay - NCBI

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Select item 19531951.

Inhibition of SGK3 (unknown origin)

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase Sgk3

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1953195

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19214022.

Induction of SGK3 degradation in HEK293 cells

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase Sgk3

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1921402

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19214003.

Induction of SGK3 degradation in HEK293 cells assessed as maximum degradation at 300 nM after 48 hrs relative to control

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase Sgk3

Assay data:1 Tested

AID:: 1921400

Summary PubMed Citation Related BioAssays by Target

Select item 19213984.

Induction of SGK3 degradation in HEK293 cells assessed as maximum degradation after 30 mins relative to control

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase Sgk3

Assay data:1 Tested

AID:: 1921398

Summary PubMed Citation Related BioAssays by Target

Select item 19142725.

Selectivity interaction (KinomeScan (DiscoverX)) EUB0000303b SGK1

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase Sgk1

Assay data:1 Tested

AID:: 1914272

Summary Related BioAssays by Target

Select item 19141616.

Selectivity interaction (Kinase panel (University of Dundee)) EUB0000169b SGK1

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase Sgk1

Assay data:1 Tested

AID:: 1914161

Summary Related BioAssays by Target

Select item 19134817.

Selectivity interaction (Kinase panel (Pfizer) ) EUB0000619a SGK1

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase Sgk1

Assay data:1 Tested

AID:: 1913481

Summary Related BioAssays by Target

Select item 19134518.

Selectivity interaction (Kinase panel (Millipore)) EUB0000153b SGK2

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase Sgk2

Assay data:1 Tested

AID:: 1913451

Summary Related BioAssays by Target

Select item 19134509.

Selectivity interaction (Kinase panel (Millipore)) EUB0000153b SGK1

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase Sgk1

Assay data:1 Tested

AID:: 1913450

Summary Related BioAssays by Target

Select item 189541710.

Inhibition of SGK1 (unknown origin) at 1 uM relative to control

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase Sgk1

Assay data:1 Tested

AID:: 1895417

Summary PubMed Citation Related BioAssays by Target

Select item 189531111.

Inhibition of SGK (unknown origin) in presence of ATP

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase Sgk1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1895311

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 188184112.

Protac activity at VHL/SGK3 in human HEK293 cells at 0.3 mM measured within 8 hrs relative to control

Source:: ChEMBL

Protein Targets:: Serine/threonine-protein kinase Sgk3; ...
Total:: 2

Assay data:1 Tested

AID:: 1881841

Summary PubMed Citation Related BioAssays by Target

Select item 188184013.

Protac activity at VHL/SGK3 in human HEK293 cells at 0.3 mM measured within 2 hrs relative to control

Source:: ChEMBL

Protein Targets:: Serine/threonine-protein kinase Sgk3; ...
Total:: 2

Assay data:1 Tested

AID:: 1881840

Summary PubMed Citation Related BioAssays by Target

Select item 185563914.

Inhibition of SGK (unknown origin) at 1 uM

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase Sgk1

Assay data:1 Tested

AID:: 1855639

Summary PubMed Citation Related BioAssays by Target

Select item 184993515.

PROTAC activity at VHL/SGK3 (unknown origin) assessed as induction of SGK3 degradation incubated for 2 hrs by cell based assay

Source:: ChEMBL

Protein Targets:: Serine/threonine-protein kinase Sgk3; ...
Total:: 2

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1849935

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 183580116.

SGK2 DiscoveRx kinase panel

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase Sgk2

Assay data:1 Tested

AID:: 1835801

Summary Related BioAssays by Target

Select item 183566417.

SGK3 DiscoveRx kinase panel

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase Sgk3

Assay data:1 Tested

AID:: 1835664

Summary Related BioAssays by Target

Select item 183560118.

SGK DiscoveRx kinase panel

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase Sgk1

Assay data:1 Tested

AID:: 1835601

Summary Related BioAssays by Target

Select item 183515419.

SGK3(h) Kinase panel

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase Sgk3

Assay data:1 Tested

AID:: 1835154

Summary Related BioAssays by Target

Select item 183515320.

SGK2(h) Kinase panel

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase Sgk2

Assay data:1 Tested

AID:: 1835153

Summary Related BioAssays by Target

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Proteins (4)
BioAssays with protein sequences specified as targets

BioActivity

Active Compounds (79)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (8)
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Activity (IC50, etc) ≤ 1 µM (63)
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Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations

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BioAssays extracted from the literature
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Related BioAssays, by Target Similarity (List) for PubChem BioAss... (688)
Related BioAssays, by Target Similarity (List) for PubChem BioAssay (Select 1953195)
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PubChem BioAssay
Profile neighbors for GEO Profiles (Select 13296762) (40)
GEO Profiles
Chromosome neighbors for GEO Profiles (Select 88407761) (19)
GEO Profiles
STX5 syntaxin 5 [Homo sapiens]
STX5 syntaxin 5 [Homo sapiens]
Gene ID:6811

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Gene Links for GEO Profiles (Select 88397278) (1)
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