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Inhibition of bovine brain tubulin assembly
Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Displacement of [3H]colchicine from bovine brain tubulin at 5 uM incubated for 10 mins
Assay data:20 Tested
SummaryPubMed CitationRelated BioAssays by Target
Displacement of [3H]colchicine from bovine brain tubulin at 0.5 uM incubated for 10 mins
Assay data:1 Tested
Inhibition of tubulin polymerization (unknown origin) by fluorescence assay relative to control
Assay data:2 Tested
Inhibition of tubulin polymerization (unknown origin) incubated for 15 mins followed by GTP addition and measured for 20 mins by spectrophotometry
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Induction of microtubule stabilization in human HeLa cells assessed as effect on cellular cytoskeletal network of tubulin at 5 to 10 uM incubated for 4 hrs by Alexa Fluor 488 staining based confocal microscopic analysis
Assay data:2 Active, 2 Tested
Induction of microtubule stabilization (unknown origin) at 1 to 5 uM
Induction of microtubule stabilization (unknown origin) at 0.2 to 5 uM
Induction of microtubule destabilization (unknown origin) at 5 uM
Induction of microtubule stabilization (unknown origin) at 5 uM
Inhibition of pig brain tubulin polymerization at 3 uM measured after 15 mins by fluorescence based turbidimetry
Inhibition of pig brain tubulin polymerization at 25 uM measured after 15 mins by fluorescence based turbidimetry
Assay data:8 Active, 10 Tested
Inhibition of tubulin polymerization in human HCT-116 cells
Inhibition of tubulin polymerization in human HCT-116 cells at 0.55 uM measured after 1 hr relative to control
Inhibition of tubulin polymerization in human HCT-116 cells at 6.50 uM measured after 1 hr relative to control
Inhibition of tubulin polymerization in human HCT-116 cells at 3.25 uM measured after 1 hr relative to control
Inhibition of tubulin polymerization in human HCT-116 cells at 1.62 uM measured after 1 hr relative to control
Inhibition of tubulin polymerization in human HCT-116 cells at 3 uM measured after 1 hr relative to control
Inhibition of tubulin polymerization (unknown origin) at 3 uM measured after 1 hr relative to control
Inhibition of tubulin polymerization (unknown origin)
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