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Inhibition of Trypanosoma brucei TryR
Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of Trypanosoma cruzi TryR assessed as inhibition constant by TR assay
Assay data:2 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of Trypanosoma cruzi TryR measured after 15 mins in presence of NADPH
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of Trypanosoma cruzi TryR assessed as inhibition constant
Assay data:4 Active, 11 Tested
Inhibition of Trypanosoma cruzi TryR assessed as inhibition constant in presence of NADPH
Assay data:4 Tested
Inhibition of Trypanosoma cruzi TryR
Assay data:6 Active, 5 Activity ≤ 1 µM, 6 Tested
Inhibition of Crithidia fasciculata TryR overexpressed in escherichia coli assessed as inhibition constant
Assay data:1 Active, 2 Tested
Inhibition of Trypanosoma cruzi TryR expressed in escherichia coli SG5
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of Trypanosoma brucei TryR assessed as inhibition constant
Assay data:2 Active, 1 Activity ≤ 1 µM, 5 Tested
Inhibition of Trypanosoma cruzi TryR expressed in escherichia coli in presence of NADPH
Assay data:1 Tested
Inhibition of HIS-tagged recombinant Trypanosoma cruzi TryR oxidoreductase activity expressed in Escherichia coli in the presence of NADPH by spectrophotometry based DTNB-coupled assay
Assay data:2 Active, 3 Tested
Inhibition of HIS-tagged recombinant Trypanosoma brucei TryR oxidoreductase activity expressed in Escherichia coli in the presence of NADPH by spectrophotometry based DTNB-coupled assay
Inhibition of Trypanosoma cruzi TR assessed as inhibition constant
Inhibition of Trypanosoma cruzi TR assessed as inhibition constant in presence of NADPH
Assay data:2 Active, 2 Tested
Inhibition of recombinant Leishmania donovani trypanothione reductase expressed in Escherichia coli BL21 (DE3) cells using trypanothione disulfide as substrate at 5 to 100 uM preincubated for 5 mins followed by substrate addition in presence of NADPH by DTNB based colorimetric assay
Inhibition of Leishmania donovani trypanothione reductase expressed in Escherichia coli BL21(DE3) using TS2 and NADPH as substrate at 100 uM preincubated for 5 mins followed by substrate addition by DTNB-reagent based spectrophotometric method
Inhibition of Trypanosoma brucei Trypanothione reductase at 200 uM in presence of NADPH by spectrophotometry
Inhibition Assay from Article 10.3109/14756369809035823: "Trypanocidal bisbenzylisoquinoline alkaloids are inhibitors of trypanothione reductase."
Assay data:10 Tested
TryR Enzyme Inhibition Assay from Article 10.1021/jm801306g: "Development of a novel virtual screening cascade protocol to identify potential trypanothione reductase inhibitors."
Assay data:19 Tested
Inhibition of Trypanosoma brucei TryR oxidoreductase activity using TS2 as substrate by spectrophotometric assay
Assay data:4 Active, 1 Activity ≤ 1 µM, 7 Tested
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