Related BioAssays, by Target Similarity (List) for PubChem BioAssay (S - PubChem BioAssay - NCBI

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Select item 19635991.

GABAA (α1β2γ2) Receptor Current using Patch-Clamp Technique from US Patent US20240132445: "PHENOL DERIVATIVE AND APPLICATION THEREOF IN MEDICAMENTS"

Source:: BindingDB

Protein Targets:: Gamma-aminobutyric acid receptor subunit alpha-1; ...
Total:: 3

Assay data:1 Active, 2 Tested

AID:: 1963599

Summary Compounds, Active Related BioAssays by Target

Select item 19634762.

Binding Assay from US Patent US20240067637: "NAPHTHYRIDINE AND PYRIDO[3,4-c]PYRIDAZINE DERIVATIVES AS GABAA ALPHA 5 RECEPTOR MODULATORS"

Source:: BindingDB

Protein Targets:: Gamma-aminobutyric acid receptor subunit alpha-5; ...
Total:: 1

Assay data:44 Active, 1 Activity ≤ 1 nM, 44 Activity ≤ 1 µM, 44 Tested

AID:: 1963476

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 19634713.

Patch Clamp Electrophysiology from US Patent US11912737: "19-nor neuroactive steroids and methods of use thereof"

Source:: BindingDB

Protein Targets:: Gamma-aminobutyric acid receptor subunit alpha-1; ...
Total:: 3

Assay data:2 Active, 3 Tested

AID:: 1963471

Summary Compounds, Active Related BioAssays by Depositor Related BioAssays by Target

Select item 19634704.

Steroid Inhibition of TBPS Binding from US Patent US11912737: "19-nor neuroactive steroids and methods of use thereof"

Source:: BindingDB

Protein Targets:: Gamma-aminobutyric acid receptor subunit alpha-1; ...
Total:: 1

Assay data:4 Active, 47 Activity ≤ 1 µM, 47 Tested

AID:: 1963470

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Depositor Related BioAssays by Target

Select item 19633715.

Binding Assay from US Patent US20240043418: "1,3-DIHYDRO-2H-PYRROLO[3,4-C]PYRIDINE DERIVATIVES AS GABAA A5 RECEPTOR MODULATORS"

Source:: BindingDB

Protein Targets:: Gamma-aminobutyric acid receptor subunit alpha-5; ...
Total:: 3

Assay data:3 Active, 1 Activity ≤ 1 nM, 3 Activity ≤ 1 µM, 3 Tested

AID:: 1963371

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 19632466.

Cross screening panel

Source:: ChEMBL

Protein Targets:: Gamma-aminobutyric acid receptor subunit alpha-3; ...
Total:: 16

Assay data:1 Tested

AID:: 1963246

Summary Related BioAssays by Target

Select item 19632457.

Cross screening panel

Source:: ChEMBL

Protein Targets:: Gamma-aminobutyric acid receptor subunit alpha-2; ...
Total:: 16

Assay data:1 Tested

AID:: 1963245

Summary Related BioAssays by Target

Select item 19632448.

Cross screening panel

Source:: ChEMBL

Protein Targets:: Gamma-aminobutyric acid receptor subunit alpha-5; ...
Total:: 16

Assay data:1 Tested

AID:: 1963244

Summary Related BioAssays by Target

Select item 19631989.

Cross screening panel

Source:: ChEMBL

Protein Targets:: Gamma-aminobutyric acid receptor subunit alpha-1; ...
Total:: 16

Assay data:1 Tested

AID:: 1963198

Summary Related BioAssays by Target

Select item 196319710.

Cross screening panel

Source:: ChEMBL

Protein Targets:: Gamma-aminobutyric acid receptor subunit alpha-2; ...
Total:: 16

Assay data:1 Tested

AID:: 1963197

Summary Related BioAssays by Target

Select item 196319611.

Cross screening panel

Source:: ChEMBL

Protein Targets:: Gamma-aminobutyric acid receptor subunit alpha-5; ...
Total:: 16

Assay data:1 Tested

AID:: 1963196

Summary Related BioAssays by Target

Select item 196252812.

GABAA, Muscimol, Central Eurofins Panlabs panel

Source:: ChEMBL

Protein Targets:: GABA theta subunit; ...
Total:: 16

Assay data:1 Tested

AID:: 1962528

Summary Related BioAssays by Target

Select item 196252613.

GABAA, Flunitrazepam, Central Eurofins Panlabs panel

Source:: ChEMBL

Protein Targets:: GABA theta subunit; ...
Total:: 16

Assay data:1 Tested

AID:: 1962526

Summary Related BioAssays by Target

Select item 196252514.

GABAA, Chloride Channel, TBOB Eurofins Panlabs panel

Source:: ChEMBL

Protein Targets:: GABA theta subunit; ...
Total:: 16

Assay data:1 Tested

AID:: 1962525

Summary Related BioAssays by Target

Select item 196237215.

BZD/CENTR/R Eurofins SafetyScreen44 (BI)

Source:: ChEMBL

Protein Targets:: GABA theta subunit; ...
Total:: 16

Assay data:1 Tested

AID:: 1962372

Summary Related BioAssays by Target

Select item 196232316.

BZD/CENTR/R Eurofins SafetyScreen44 (BI)

Source:: ChEMBL

Protein Targets:: GABA theta subunit; ...
Total:: 16

Assay data:1 Tested

AID:: 1962323

Summary Related BioAssays by Target

Select item 196222317.

BZD/CENTR/R Eurofins SafetyScreen44 (BI)

Source:: ChEMBL

Protein Targets:: GABA theta subunit; ...
Total:: 16

Assay data:1 Tested

AID:: 1962223

Summary Related BioAssays by Target

Select item 196217818.

BZD/CENTR/R Eurofins SafetyScreen44 (BI)

Source:: ChEMBL

Protein Targets:: GABA theta subunit; ...
Total:: 16

Assay data:1 Tested

AID:: 1962178

Summary Related BioAssays by Target

Select item 196216119.

BZD/CENTR/R Eurofins SafetyScreen44 (BI)

Source:: ChEMBL

Protein Targets:: GABA theta subunit; ...
Total:: 16

Assay data:1 Tested

AID:: 1962161

Summary Related BioAssays by Target

Select item 196208220.

BZD/CENTR/R Eurofins SafetyScreen44 (BI)

Source:: ChEMBL

Protein Targets:: GABA theta subunit; ...
Total:: 16

Assay data:1 Tested

AID:: 1962082

Summary Related BioAssays by Target

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Proteins (560)
BioAssays with protein sequences specified as targets

BioActivity

Active Compounds (1,021)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (217)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (839)
BioAssays with the active concentration of tested reagents less than 1 micromolar

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Confirmatory (1,131)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (1)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose

Assay Project (14)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (2,380)
BioAssays extracted from the literature
NIH MLP (14)
BioAssays deposited by the NIH Molecular Libraries Program
Other (119)
BioAssays deposited by other experimentalists

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Related BioAssays, by Target Similarity (List) for PubChem BioAss... (2513)
Related BioAssays, by Target Similarity (List) for PubChem BioAssay (Select 1962323)
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PubChem BioAssay
tyrosine-protein kinase Tec isoform X5 [Rattus norvegicus]
tyrosine-protein kinase Tec isoform X5 [Rattus norvegicus]
gi|1958677440|ref|XP_038948442.1|

Protein
"1261739-69-8"[CompleteSynonym] (1)
PubChem Compound

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