Related BioAssays, by Target Similarity (List) for PubChem BioAssay (S - PubChem BioAssay - NCBI

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Select item 19624791.

Panlabs assay PDE9A2

Source:: ChEMBL

Protein Target:: High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A

Assay data:1 Tested

AID:: 1962479

Summary Related BioAssays by Target

Select item 19624542.

3H-cAMP and 3H-cGMP Scintillation Proximity Assay (PDE9A)

Source:: ChEMBL

Protein Target:: High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A

Assay data:1 Active, 1 Activity ≤ 1 µM, 2 Tested

AID:: 1962454

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 19607163.

Inhibition of PDE9A (unknown origin) by 3H-cAMP scintillation proximity assay

Source:: ChEMBL

Protein Target:: High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A

Assay data:1 Tested

AID:: 1960716

Summary PubMed Citation Related BioAssays by Target

Select item 19300274.

Inhibition of human PDE9A expressed in Escherichia coli DH10 by scintillation proximity assay

Source:: ChEMBL

Protein Target:: High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1930027

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19235805.

Inhibition of recombinant PDE9A (181 to 506 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H]-cGMP as substrate measured for 15 mins by liquid scintillation counter method

Source:: ChEMBL

Protein Target:: High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A

Assay data:4 Active, 2 Activity ≤ 1 µM, 4 Tested

AID:: 1923580

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19235796.

Inhibition of PDE9 (unknown origin) using 3[H]-cGMP as substrate incubated for 15 mins by liquid scintillation counter

Source:: ChEMBL

Protein Target:: High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1923579

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19235437.

Inhibition of PDE9A (unknown origin)

Source:: ChEMBL

Protein Target:: High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A

Assay data:3 Active, 3 Activity ≤ 1 µM, 4 Tested

AID:: 1923543

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19193578.

PDE9 Inhibition Assay from US Patent US11608342: "PDE9 inhibitors with imidazo triazinone backbone and imidazo pyrazinone backbone for treatment of peripheral diseases"

Source:: BindingDB

Protein Targets:: High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A; ...
Total:: 1

Assay data:5 Active, 5 Activity ≤ 1 µM, 5 Tested

AID:: 1919357

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Depositor Related BioAssays by Target

Select item 19169149.

Inhibition of PDE9A (unknown origin)

Source:: ChEMBL

Protein Target:: High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A

Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested

AID:: 1916914

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 191467110.

Selectivity interaction (PDE panel (enzymatic activity assay)) EUB0000751a PDE9A

Source:: ChEMBL

Protein Target:: High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A

Assay data:1 Tested

AID:: 1914671

Summary Related BioAssays by Target

Select item 191461911.

Selectivity interaction (PDE panel (enzymatic assay)) EUB0000744a PDE9A

Source:: ChEMBL

Protein Target:: High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A

Assay data:1 Tested

AID:: 1914619

Summary Related BioAssays by Target

Select item 191209812.

Inhibition of PDE9A (181 to 506 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H]-cGMP as substrate at 10000 nM measured for 15 mins by liquid scintillation counter method

Source:: ChEMBL

Protein Target:: High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A

Assay data:1 Tested

AID:: 1912098

Summary PubMed Citation Related BioAssays by Target

Select item 191204313.

Inhibition of PDE9A2 (181 to 506 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H]-cGMP as substrate measured for 15 mins by liquid scintillation counter method

Source:: ChEMBL

Protein Target:: High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A

Assay data:1 Tested

AID:: 1912043

Summary PubMed Citation Related BioAssays by Target

Select item 190294014.

Inhibition of PDE9A2 (181 to 506 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H-GMP] or [3H-AMP] as substrate incubated for 15 mins by liquid scintillation counting method

Source:: ChEMBL

Protein Target:: High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A

Assay data:1 Tested

AID:: 1902940

Summary PubMed Citation Related BioAssays by Target

Select item 189792915.

Inhibition of rat PDE9A using [3H]-cGMP as substrate at 42 nM incubated for 60 mins by microbeta scintillation counter analysis relative to control

Source:: ChEMBL

Protein Target:: High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A

Assay data:1 Tested

AID:: 1897929

Summary PubMed Citation Related BioAssays by Target

Select item 189788316.

Inhibition of full length human PDE9A expressed in Sf9 insect cells using [3H]-cGMP as substrate incubated for 60 mins by microbeta scintillation counter analysis

Source:: ChEMBL

Protein Target:: High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A

Assay data:33 Active, 32 Activity ≤ 1 µM, 34 Tested

AID:: 1897883

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 189583817.

Inhibition of PDE9A (unknown origin)

Source:: ChEMBL

Protein Target:: High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1895838

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 189583518.

Inhibition of PDE9 in human SH-SY5Y cells measured after 2 hrs by Western blot analysis

Source:: ChEMBL

Protein Target:: High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1895835

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 188458619.

Inhibition of PDE9A2 (unknown origin)

Source:: ChEMBL

Protein Target:: High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A

Assay data:1 Tested

AID:: 1884586

Summary PubMed Citation Related BioAssays by Target

Select item 188231920.

Inhibition of PDE9 (unknown origin)

Source:: ChEMBL

Protein Target:: High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1882319

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

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BioAssays with protein sequences specified as targets

BioActivity

Active Compounds (82)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (11)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (80)
BioAssays with the active concentration of tested reagents less than 1 micromolar

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Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations

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BioAssays extracted from the literature
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Related BioAssays, by Target Similarity (List) for PubChem BioAss... (193)
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PubChem BioAssay
THAP6 THAP domain containing 6 [Homo sapiens]
THAP6 THAP domain containing 6 [Homo sapiens]
Gene ID:152815

Gene
Gene Links for GEO Profiles (Select 72032124) (1)
Gene
G3BP2 G3BP stress granule assembly factor 2 [Homo sapiens]
G3BP2 G3BP stress granule assembly factor 2 [Homo sapiens]
Gene ID:9908

Gene
Gene Links for GEO Profiles (Select 72010957) (1)
Gene

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