Related BioAssays, by Target Similarity (List) for PubChem BioAssay (S - PubChem BioAssay - NCBI

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Select item 19637631.

In Vitro Detection of the Inhibitory Activity of Compounds Against PDE 3A Enzyme from US Patent US11993596: "Fused tri-cyclic compound as PDE3/PDE4 dual inhibitor"

Source:: BindingDB

Protein Targets:: cGMP-inhibited 3',5'-cyclic phosphodiesterase A; ...
Total:: 1

Assay data:29 Active, 28 Activity ≤ 1 nM, 29 Activity ≤ 1 µM, 29 Tested

AID:: 1963763

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Depositor Related BioAssays by Target

Select item 19632652.

Cross screening panel

Source:: ChEMBL

Protein Target:: cGMP-inhibited 3',5'-cyclic phosphodiesterase A

Assay data:1 Tested

AID:: 1963265

Summary Related BioAssays by Target

Select item 19632163.

Cross screening panel

Source:: ChEMBL

Protein Target:: cGMP-inhibited 3',5'-cyclic phosphodiesterase A

Assay data:1 Tested

AID:: 1963216

Summary Related BioAssays by Target

Select item 19631684.

Cross screening panel

Source:: ChEMBL

Protein Target:: cGMP-inhibited 3',5'-cyclic phosphodiesterase A

Assay data:1 Tested

AID:: 1963168

Summary Related BioAssays by Target

Select item 19630835.

Safety47 Scan (DiscoverX - Eurofins)

Source:: ChEMBL

Protein Target:: cGMP-inhibited 3',5'-cyclic phosphodiesterase A

Assay data:1 Tested

AID:: 1963083

Summary Related BioAssays by Target

Select item 19624966.

Phosphodiesterase PDE3 Eurofins Panlabs panel

Source:: ChEMBL

Protein Targets:: cGMP-inhibited 3',5'-cyclic phosphodiesterase A; ...
Total:: 2

Assay data:1 Tested

AID:: 1962496

Summary Related BioAssays by Target

Select item 19624687.

Panlabs assay PDE3A

Source:: ChEMBL

Protein Target:: cGMP-inhibited 3',5'-cyclic phosphodiesterase A

Assay data:1 Tested

AID:: 1962468

Summary Related BioAssays by Target

Select item 19623968.

PDE3A Eurofins SafetyScreen44 (BI)

Source:: ChEMBL

Protein Target:: cGMP-inhibited 3',5'-cyclic phosphodiesterase A

Assay data:1 Tested

AID:: 1962396

Summary Related BioAssays by Target

Select item 19623479.

PDE3A Eurofins SafetyScreen44 (BI)

Source:: ChEMBL

Protein Target:: cGMP-inhibited 3',5'-cyclic phosphodiesterase A

Assay data:1 Tested

AID:: 1962347

Summary Related BioAssays by Target

Select item 196224910.

PDE3A Eurofins SafetyScreen44 (BI)

Source:: ChEMBL

Protein Target:: cGMP-inhibited 3',5'-cyclic phosphodiesterase A

Assay data:1 Tested

AID:: 1962249

Summary Related BioAssays by Target

Select item 196220211.

PDE3A Eurofins SafetyScreen44 (BI)

Source:: ChEMBL

Protein Target:: cGMP-inhibited 3',5'-cyclic phosphodiesterase A

Assay data:1 Tested

AID:: 1962202

Summary Related BioAssays by Target

Select item 196214112.

PDE3A Eurofins SafetyScreen44 (BI)

Source:: ChEMBL

Protein Target:: cGMP-inhibited 3',5'-cyclic phosphodiesterase A

Assay data:1 Tested

AID:: 1962141

Summary Related BioAssays by Target

Select item 196210613.

PDE3A Eurofins SafetyScreen44 (BI)

Source:: ChEMBL

Protein Target:: cGMP-inhibited 3',5'-cyclic phosphodiesterase A

Assay data:1 Tested

AID:: 1962106

Summary Related BioAssays by Target

Select item 196206214.

PDE3A Eurofins SafetyScreen44 (BI)

Source:: ChEMBL

Protein Target:: cGMP-inhibited 3',5'-cyclic phosphodiesterase A

Assay data:1 Tested

AID:: 1962062

Summary Related BioAssays by Target

Select item 196185515.

Compound was evaluated for inhibition of human PDE3A in an in vitro cell free assay measured by time-resolved fluorescence resonance energy transfer method

Source:: ChEMBL

Protein Target:: cGMP-inhibited 3',5'-cyclic phosphodiesterase A

Assay data:49 Active, 5 Activity ≤ 1 µM, 1243 Tested

AID:: 1961855

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 196181316.

Compound was evaluated for inhibition of human PDE3A in an in vitro cell free assay measured by time-resolved fluorescence resonance energy transfer method

Source:: ChEMBL

Protein Target:: cGMP-inhibited 3',5'-cyclic phosphodiesterase A

Assay data:15 Active, 6 Activity ≤ 1 µM, 927 Tested

AID:: 1961813

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 196125517.

Inhibition of PDE3A (unknown origin) upto 10000 nM

Source:: ChEMBL

Protein Target:: cGMP-inhibited 3',5'-cyclic phosphodiesterase A

Assay data:1 Tested

AID:: 1961255

Summary PubMed Citation Related BioAssays by Target

Select item 196072618.

Inhibition of human N-terminal His-GST-tagged recombinant PDE3A (669-end residues) using fluorescent labelled cAMP as substrate

Source:: ChEMBL

Protein Target:: cGMP-inhibited 3',5'-cyclic phosphodiesterase A

Assay data:7 Active, 6 Activity ≤ 1 µM, 7 Tested

AID:: 1960726

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 196068919.

Inhibition of PDE3A (unknown origin) by 3H-cAMP scintillation proximity assay

Source:: ChEMBL

Protein Target:: cGMP-inhibited 3',5'-cyclic phosphodiesterase A

Assay data:1 Tested

AID:: 1960689

Summary PubMed Citation Related BioAssays by Target

Select item 195269320.

Binding affinity to PDE3A (unknown origin) assessed as dissociation constant

Source:: ChEMBL

Protein Target:: cGMP-inhibited 3',5'-cyclic phosphodiesterase A

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1952693

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

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BioAssays with protein sequences specified as targets

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Active Compounds (183)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (13)
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Activity (IC50, etc) ≤ 1 µM (129)
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Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations

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Literature Extraction (436)
BioAssays extracted from the literature
Other (37)
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