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Inhibition of BRD9 in human Kasumi-1 cells assessed as downregulation of SAMSN1 gene at 1 uM after 6 hrs by qPCR method
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of BRD9 in human Kasumi-1 cells assessed as downregulation of FES gene at 1 uM after 6 hrs by qPCR method
Inhibition of BRD9 in human Kasumi-1 cells assessed as downregulation of DUSP6 gene at 1 uM after 6 hrs by qPCR method
Inhibition of BRD9 in human Kasumi-1 cells assessed as downregulation of CLEC1 gene at 1 uM after 6 hrs by qPCR method
Inhibition of BRD9 in human Kasumi-1 cells assessed as downregulation of SAMSN1 gene at 10 uM after 6 hrs by qPCR method
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of BRD9 in human Kasumi-1 cells assessed as downregulation of FES gene at 10 uM after 6 hrs by qPCR method
Inhibition of BRD9 in human Kasumi-1 cells assessed as downregulation of DUSP6 gene at 10 uM after 6 hrs by qPCR method
Inhibition of BRD9 in human Kasumi-1 cells assessed as downregulation of CLEC1 gene at 10 uM after 6 hrs by qPCR method
PROTAC activity at VHL/BRD9 in human A204 cells assessed as BRD9 protein degradation incubated for 18 hrs by WES capillary electrophoresis analysis
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
PROTAC activity at VHL/BRD9 in human EOL1 cells assessed as BRD9 protein degradation incubated for 18 hrs by WES capillary electrophoresis analysis
PROTAC activity at VHL/HiBit-tagged BRD9 in HEK293 cells assessed as BRD9 protein degradation pre-incubated with endurazine for 2.5 hrs followed by compound addition and measured after 24 hrs by live cell kinetics assay
PROTAC activity at VHL/BRD9 in human Ri-1 cells assessed as maximal degradation by Western blot analysis relative to control
PROTAC activity at VHL/BRD9 in human Ri-1 cells assessed as degradation of BRD9 protein incubated for 8 hrs by Western blot analysis
PROTAC activity at VHL/BRD9 in human Ri-1 cells assessed as remaining BRD9 protein level at 1 nM incubated for 2 hrs by Western blot analysis relative to control
Assay data:2 Tested
PROTAC activity at VHL/BRD9 in human Ri-1 cells assessed as remaining BRD9 protein level at 10 nM incubated for 2 hrs by Western blot analysis relative to control
PROTAC activity at VHL/BRD9 in human Ri-1 cells assessed as remaining BRD9 protein level at 100 nM incubated for 2 hrs by Western blot analysis relative to control
PROTAC activity at VHL/BRD9 in human Ri-1 cells assessed as remaining BRD9 protein level at 10000 nM incubated for 2 hrs by Western blot analysis relative to control
PROTAC activity at VHL/BRD9 in human Ri-1 cells assessed as remaining BRD9 protein level at 0.1 nM incubated for 8 hrs by Western blot analysis relative to control
PROTAC activity at VHL/BRD9 in human Ri-1 cells assessed as remaining BRD9 protein level at 1 nM incubated for 8 hrs by Western blot analysis relative to control
PROTAC activity at VHL/BRD9 in human Ri-1 cells assessed as remaining BRD9 protein level at 10 nM incubated for 8 hrs by Western blot analysis relative to control
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