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CDK4/CyclinD1 Kinase Inhibitory Activity Assay from US Patent US20240166635: "AMINOHETEROARYL KINASE INHIBITORS"
Assay data:110 Active, 119 Activity ≤ 1 µM, 119 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
CDK6/CyclinD1 Kinase Inhibitory Activity Assay from US Patent US20240166635: "AMINOHETEROARYL KINASE INHIBITORS"
Assay data:124 Active, 133 Activity ≤ 1 µM, 133 Tested
CDK Inhibition In Vitro Assay from US Patent US20240150369: "CYCLIN-DEPENDENT KINASE INHIBITING COMPOUNDS FOR THE TREATMENT OF MEDICAL DISORDERS"
Assay data:31 Active, 8 Activity ≤ 1 nM, 31 Activity ≤ 1 µM, 31 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
CDK6/Cyclin D3 ADP-Glo Kinase Assay from US Patent US20240092761: "QUINAZOLINE COMPOUNDS AND METHODS OF USE"
Assay data:67 Active, 67 Activity ≤ 1 µM, 67 Tested
CDK4/Cyclin D1 (Chelation-Enhance Fluorescence)(CHEF) Assay from US Patent US20240092761: "QUINAZOLINE COMPOUNDS AND METHODS OF USE"
Assay data:116 Active, 99 Activity ≤ 1 µM, 122 Tested
CDK4/Cyclin D1 Mobility Shift Assay (MSA) from US Patent US20240092761: "QUINAZOLINE COMPOUNDS AND METHODS OF USE"
Assay data:55 Active, 49 Activity ≤ 1 µM, 55 Tested
CDK4/Cyclin D1 CHEF Assay from US Patent US20240034731: "AZA-QUINAZOLINE COMPOUNDS AND METHODS OF USE"
Assay data:79 Active, 76 Activity ≤ 1 µM, 81 Tested
CDK6/Cyclin D3 ADP-Glo Kinase Assay from US Patent US20240034731: "AZA-QUINAZOLINE COMPOUNDS AND METHODS OF USE"
Assay data:90 Active, 82 Activity ≤ 1 µM, 97 Tested
CDK4/Cyclin D1 Mobility Shift Assay (MSA) from US Patent US20240034731: "AZA-QUINAZOLINE COMPOUNDS AND METHODS OF USE"
Assay data:18 Active, 16 Activity ≤ 1 µM, 18 Tested
Assay for Inhibition of CDK6/CyclinD3 from US Patent US20240033264: "CDK INHIBITORS"
Assay data:4 Active, 4 Activity ≤ 1 µM, 4 Tested
Assay for Inhibition of CDK4/CyclinD1 from US Patent US20240033264: "CDK INHIBITORS"
Inhibition of full length human CDK4/N-terminal GST fused human cyclinD3 expressed in baculovirus expression system using 5-FAMIPTSPITTTYFFFKKK-COOH as substrate at 10 uM incubated for 60 mins in presence of ATP relative to control
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of full length human CDK6/N-terminal GST fused human cyclinD3 expressed in baculovirus expression system using 5-FAMIPTSPITTTYFFFKKK-COOH as substrate at 10 uM incubated for 60 mins in presence of ATP relative to control
Inhibition of full length human CDK6/N-terminal GST fused human cyclinD3 expressed in baculovirus expression system using 5-FAMIPTSPITTTYFFFKKK-COOH as substrate incubated for 60 mins in presence of ATP
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of full length human CDK4/N-terminal GST fused human cyclinD3 expressed in baculovirus expression system using 5-FAMIPTSPITTTYFFFKKK-COOH as substrate incubated for 60 mins in presence of ATP
Inhibition of CDK6/Cyclin D3 (unknown origin)
Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested
Inhibition of CDK4/Cyclin D1 (unknown origin)
Covalent inhibition of CDK6 (unknown origin) using histone H1 as substrate incubated for 10 mins in presence of [gamma-32P]ATP by radioactivity based kinase assay
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