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Biochemical Kinase Assay Protocol (JAK) from US Patent US20240132525: "BORON CONTAINING PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM, METHODS AND USES THEREOF"
Assay data:90 Active, 39 Activity ≤ 1 nM, 91 Activity ≤ 1 µM, 91 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
In vitro PDE4B Enzyme Activity Detection Assay from US Patent US20240083921: "BORATE DERIVATIVE AND USES THEREOF"
Assay data:14 Active, 12 Activity ≤ 1 nM, 14 Activity ≤ 1 µM, 14 Tested
Cross screening panel
Assay data:1 Tested
SummaryRelated BioAssays by Target
Safety47 Scan (DiscoverX - Eurofins)
Phosphodiesterase PDE4 Eurofins Panlabs panel
Panlabs assay PDE4D2
Panlabs assay PDE4C1
Panlabs assay PDE4B1
Panlabs assay PDE4A1A
3H-cAMP and 3H-cGMP Scintillation Proximity Assay (PDE4B)
PDE4D2 Eurofins SafetyScreen44 (BI)
Compound was evaluated for inhibition of human PDE4D in an in vitro cell free assay measured by scintillation proximity assay
Assay data:109 Active, 1 Activity ≤ 1 nM, 13 Activity ≤ 1 µM, 1242 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
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