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Binding Inhibition Assay from US Patent US9533985: "Sulfonamide derivative and medicinal use thereof"
Assay data:40 Active, 37 Activity ≤ 1 µM, 40 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
Inhibition of VCAM1 (unknown origin)
Assay data:2 Active, 2 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of VCAM1 in TNF-alpha/IL4-stimulated HUVEC assessed as inhibition of cell adhesion between HUVEC and Ramos cells at 8 uM after 20 hrs incubation relative to untreated control
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of TNF-alpha inducible Vascular cell adhesion molecule-1 expression.
Assay data:3 Active, 18 Tested
In vitro inhibitory potency compared to PMA induced VCAM-1 expression in human endothelial cells (ELISA assay)
In vitro inhibitory potency compared to TNF-alpha induced VCAM-1 expression in human endothelial cells (ELISA assay)
In vitro potency against TNF alpha induced expression of VCAM-1 on human vascular endothelial cells using CAM ELISA assay
Assay data:11 Active, 13 Activity ≤ 1 µM, 56 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
In vitro inhibitory potency compared to TNF-alpha induced VCAM-1 in human endothelial cells (ELISA assay)
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
In vitro inhibitory potency compared to PMA induced VCAM-1 in human endothelial cells (ELISA assay)
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
In vitro inhibitory potency compared to IL1-beta induced VCAM-1 in human endothelial cells (ELISA assay)
In vitro inhibitory potency compared to IL1-beta induced VCAM-1 expression in human endothelial cells (ELISA assay)
Assay data:1 Active, 1 Activity ≤ 1 µM, 2 Tested
In vitro inhibitory potency against VCAM-1 receptor in human endothelial cells (ELISA assay)
Assay data:2 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of VCAM-1 in human endothelial cells
Assay data:26 Active, 79 Activity ≤ 1 µM, 85 Tested
Ability to inhibit expression of Vascular cell adhesion molecule 1; No effect
Assay data:6 Tested
Ability to inhibit expression of Vascular cell adhesion molecule 1
Assay data:18 Active, 30 Tested
Confirmatory Screen for chemical potentiatiors of TNF alpha stimulated VCAM1 expression
Assay data:227 Tested
SummaryPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Primary HTS assay during TNFalpha stimulated VCAM1 expression to assess cytotoxicity.
Assay data:160 Active, 92911 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
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