Related BioAssays, by Target Similarity (List) for PubChem BioAssay (S - PubChem BioAssay - NCBI

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Select item 19143051.

Selectivity interaction (Lead profiling screen (Eurofins, enzymes, transporters, GPCRs, ion chanels)) EUB0000728a MMP16

Source:: ChEMBL

Protein Target:: Matrix metalloproteinase-16

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1914305

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 18639512.

Inhibition of MMP-16 (unknown origin) expressed in Escherichia coli BL21(DE3) and measured for 2 mins by enzymatic assay

Source:: ChEMBL

Protein Target:: Matrix metalloproteinase-16

Assay data:1 Active, 1 Tested

AID:: 1863951

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 13454513.

Human MMP16 (M10: Matrix metallopeptidase)

Source:: IUPHAR/BPS Guide to PHARMACOLOGY

Protein Target:: matrix metalloproteinase-16 precursor

Assay data:2 Active, 2 Tested

AID:: 1345451

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 12746754.

Inhibition of MMP24 (unknown origin) catalytic domain using MCA-Arg-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-Glu-Arg-NH2 as substrate preincubated for 60 mins followed by substrate addition by fluorescence assay

Source:: ChEMBL

Protein Target:: Matrix metalloproteinase-24

Assay data:1 Active, 1 Tested

AID:: 1274675

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 12746735.

Inhibition of MMP16 (unknown origin) catalytic domain using MCA-Arg-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-Glu-Arg-NH2 as substrate preincubated for 60 mins followed by substrate addition by fluorescence assay

Source:: ChEMBL

Protein Target:: Matrix metalloproteinase-16

Assay data:1 Active, 1 Tested

AID:: 1274673

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 6492036.

Inhibition of human MMP24

Source:: ChEMBL

Protein Target:: Matrix metalloproteinase-24

Assay data:1 Tested

AID:: 649203

Summary PubMed Citation Related BioAssays by Target

Select item 6492017.

Inhibition of human MMP16

Source:: ChEMBL

Protein Target:: Matrix metalloproteinase-16

Assay data:1 Tested

AID:: 649201

Summary PubMed Citation Related BioAssays by Target

Select item 6416818.

Inhibition of human recombinant MMP16 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate preincubated for 4 hrs measured every 15 secs for 20 mins by fluorescence analysis

Source:: ChEMBL

Protein Target:: Matrix metalloproteinase-16

Assay data:3 Active, 1 Activity ≤ 1 µM, 3 Tested

AID:: 641681

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 4541789.

Inhibition of MMP24

Source:: ChEMBL

Protein Target:: Matrix metalloproteinase-24

Assay data:1 Tested

AID:: 454178

Summary PubMed Citation Related BioAssays by Target

Select item 45417710.

Inhibition of MMP16

Source:: ChEMBL

Protein Target:: Matrix metalloproteinase-16

Assay data:1 Tested

AID:: 454177

Summary PubMed Citation Related BioAssays by Target

Select item 44042811.

Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetry

Source:: ChEMBL

Protein Target:: Matrix metalloproteinase-16

Assay data:16 Active, 8 Activity ≤ 1 µM, 20 Tested

AID:: 440428

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 41974412.

Inhibition of human recombinant MMP16

Source:: ChEMBL

Protein Target:: Matrix metalloproteinase-16

Assay data:3 Active, 2 Activity ≤ 1 µM, 4 Tested

AID:: 419744

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 41396213.

Inhibition of MMP16

Source:: ChEMBL

Protein Target:: Matrix metalloproteinase-16

Assay data:8 Active, 2 Activity ≤ 1 nM, 8 Activity ≤ 1 µM, 8 Tested

AID:: 413962

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 37088614.

Inhibition of human recombinant MMP24 at 200 uM by HxBPyne probe-based competitive activity based protein profiling assay in presence of 5 uM HxBpane competitor

Source:: ChEMBL

Protein Target:: Matrix metalloproteinase-24

Assay data:1 Active, 3 Tested

AID:: 370886

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 37088515.

Inhibition of human recombinant MMP16 at 200 uM by HxBPyne probe-based competitive activity based protein profiling assay in presence of 5 uM HxBpane competitor

Source:: ChEMBL

Protein Target:: Matrix metalloproteinase-16

Assay data:1 Active, 3 Tested

AID:: 370885

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 34941316.

Inhibition of MMP16

Source:: ChEMBL

Protein Target:: Matrix metalloproteinase-16

Assay data:1 Active, 4 Tested

AID:: 349413

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 34940517.

Inhibition of MMP16 up to 100 uM

Source:: ChEMBL

Protein Target:: Matrix metalloproteinase-16

Assay data:1 Tested

AID:: 349405

Summary PubMed Citation Related BioAssays by Target

Select item 31434718.

Inhibition of MMP16

Source:: ChEMBL

Protein Target:: Matrix metalloproteinase-16

Assay data:4 Tested

AID:: 314347

Summary PubMed Citation Related BioAssays by Target

Select item 26472919.

Binding affinity to MMP16

Source:: ChEMBL

Protein Target:: Matrix metalloproteinase-16

Assay data:2 Tested

AID:: 264729

Summary PubMed Citation Related BioAssays by Target

Select item 25947120.

Inhibitory activity against MMP16 upto 50uM

Source:: ChEMBL

Protein Target:: Matrix metalloproteinase-16

Assay data:5 Tested

AID:: 259471

Summary PubMed Citation Related BioAssays by Target

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Target

Proteins (1)
BioAssays with protein sequences specified as targets

BioActivity

Active Compounds (17)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (1)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (8)
BioAssays with the active concentration of tested reagents less than 1 micromolar

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Confirmatory (20)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations

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Literature Extraction (24)
BioAssays extracted from the literature
Other (1)
BioAssays deposited by other experimentalists

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Related BioAssays, by Target Similarity (List) for PubChem BioAss... (25)
Related BioAssays, by Target Similarity (List) for PubChem BioAssay (Select 370886)
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PubChem BioAssay
PREDICTED: Homo sapiens tenascin C (TNC), transcript variant X9, mRNA
PREDICTED: Homo sapiens tenascin C (TNC), transcript variant X9, mRNA
gi|2462624484|ref|XM_054362867.1|

Nucleotide
LOC101928957 [Homo sapiens]
LOC101928957 [Homo sapiens]
Gene ID:101928957

Gene

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