Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Binding affinity to recombinant Shigella dysenteriae type 1 Shiga toxin A subunit assessed as fast off rate constant by SPR method
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Binding affinity to recombinant Shigella dysenteriae type 1 Shiga toxin A subunit assessed as fast on rate constant by SPR method
Binding affinity to recombinant Shigella dysenteriae type 1 Shiga toxin A subunit by SPR method
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of Shigella dysenteriae type 1 Shiga toxin A subunit in African green monkey Vero cells assessed as inhibition of Stx-induced cytotoxicity pre-treated with compound for 1 hr followed by Stx exposure for 24 hrs by neutral red uptake assay
Assay data:4 Active, 9 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of Shigella dysenteriae type 1 Shiga toxin A subunit in African green monkey Vero cells assessed as protection of cell membrane integrity pre-treated with compound for 1 hr followed by Stx exposure for 24 hrs by LDH release assay relative to untreated control
Assay data:6 Active, 6 Tested
Inhibition of Shigella dysenteriae type 1 Shiga toxin A subunit in African green monkey Vero cells assessed as inhibition of Stx-induced cytotoxicity pre-treated with compound for 1 hr followed by Stx exposure for 24 hrs by LDH release assay relative to untreated control
Inhibition of Shigella dysenteriae type 1 Shiga toxin A subunit in African green monkey Vero cells assessed as inhibition of Stx-induced cytotoxicity pre-treated with compound for 1 hr followed by Stx exposure for 24 hrs by MTT assay relative to untreated control
Inhibition of Shigella dysenteriae type 1 Shiga toxin A subunit in African green monkey Vero cells assessed as inhibition of Stx-induced cytotoxicity pre-treated with compound for 1 hr followed by Stx exposure for 24 hrs by neutral red uptake assay relative to untreated control
Assay data:6 Tested
Inhibition of Shigella dysenteriae type 1 Shiga toxin A subunit assessed as change in transition temperature by SYPRO orange dye based fluorescence-based thermal shift assay
Assay data:8 Active, 20 Tested
Inhibition of Shigella dysenteriae type 1 Shiga toxin A subunit
Assay data:23 Tested
Concentration response confirmation assay for small molecule inhibitors of Shiga toxin
Assay data:4 Active, 1 Activity ≤ 1 µM, 32 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Concentration response cycloheximide confirmation counterscreen for small molecule inhibitors of Shiga toxin
Assay data:31 Tested
SummaryPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
A qHTS for Small Molecule Inhibitors of Shiga Toxin (Summary)
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
A qHTS for Small Molecule Inhibitors of Shiga Toxin (Confirmatory)
Assay data:100 Active, 14 Activity ≤ 1 nM, 125 Activity ≤ 1 µM, 506 Tested
Cycloheximide Counterscreen for Small Molecule Inhibitors of Shiga Toxin (Confirmatory)
Assay data:17 Active, 6 Activity ≤ 1 µM, 506 Tested
A qHTS for Small Molecule Inhibitors of Shiga Toxin
Assay data:26913 Active, 293642 Tested
Cycloheximide Counterscreen for Small Molecule Inhibitors of Shiga Toxin
Assay data:37055 Active, 296456 Tested
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on