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Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) by Lineweaver-Burk plot analysis
Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Non-competitive inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) by Lineweaver-Burk plot analysis
Assay data:3 Active, 2 Activity ≤ 1 µM, 3 Tested
Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) assessed as formation of DHNA-CoA from OSB-CoA at 50 uM by enzyme coupled-assay in presence of Escherichia coli MenE
Assay data:2 Active, 8 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) assessed as formation of DHNA-CoA from OSB-CoA up to 300 uM by enzyme coupled-assay in presence of Escherichia coli MenE
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) assessed as formation of DHNA-CoA from OSB-CoA by enzyme coupled-assay in presence of Escherichia coli MenE
Assay data:8 Active, 7 Activity ≤ 1 µM, 18 Tested
Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) assessed as formation of DHNA-CoA from OSB-CoA by enzyme coupled-assay in presence of Escherichia coli MenE preincubated for 1 hr
Assay data:2 Active, 6 Tested
A screen for compounds that inhibit the MenB enzyme of Mycobacterium tuberculosis
Assay data:440 Active, 103205 Tested
Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) up to 100 uM by double-reciprocal plot analysis
Assay data:7 Tested
Non-competitive inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) assessed as inhibition of enzyme-substrate complex formation
Assay data:3 Tested
Non-competitive inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3)
Assay data:1 Active, 3 Tested
Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) by double-reciprocal plot analysis
Assay data:1 Active, 13 Tested
Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) at 125 ug/ml by double-reciprocal plot analysis
Assay data:4 Tested
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