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Cross screening panel
Assay data:1 Tested
SummaryRelated BioAssays by Target
Assay data:1 Active, 1 Tested
hABHD12 Endocannabinoid related and lipase panel
hABHD6 Endocannabinoid related and lipase panel
hFAAH Endocannabinoid related and lipase panel
Safety47 Scan (DiscoverX - Eurofins)
Cholinesterase, Acetyl, ACES Eurofins Panlabs panel
Compound was evaluated for inhibition of human ACHE in an vitro cell free assay measured by absorbance method
Assay data:10 Active, 5 Activity ≤ 1 µM, 73 Tested
Assay data:31 Active, 15 Activity ≤ 1 µM, 927 Tested
Inhibition of AChE (unknown origin) upto 10000 nM
Inhibition of AChE (unknown origin) by UV spectrophotometric analysis
Assay data:9 Active, 9 Activity ≤ 1 µM, 9 Tested
Inhibition of AChE (unknown origin)
Assay data:13 Active, 13 Activity ≤ 1 µM, 14 Tested
Inhibition of Fatty acid synthase in chicken liver using [3H]-acetyl CoA as substrate preincubated for 30 mins followed by substrate addition and measured after 10 mins in presence of NADPH by scintillation counting analysis
Assay data:5 Tested
Inhibition of human AchE
Inhibition of recombinant human HTRA2 using H2-OPT as substrate assessed as increase in fluorescence at 1 uM and measured for 2 hrs by fluorescent plate reader analysis
Inhibition of recombinant human HTRA2 using H2-OPT as substrate assessed as increase in fluorescence and measured for 2 hrs by fluorescent plate reader analysis
Assay data:5 Active, 10 Tested
Binding affinity to recombinant human HTRA2 assessed as increase in fluorescence using H2-OPT as substrate at 1 uM by SDS-PAGE based gel fluorescence scanning analysis
Assay data:6 Active, 9 Tested
Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested
Inhibition of human AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 20 mins followed by substrate addition and measured for 5 mins by Ellman's spectrophotometric method
Assay data:19 Active, 5 Activity ≤ 1 µM, 20 Tested
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