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Inhibition of recombinant soluble human PC7 using pyroGlu-Arg-Thr-Lys-Arg-methyl-coumaryl-7-amide as substrate measured after 1 hr
Assay data:4 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of recombinant C-terminal truncated human SPC7 expressed in drosophila Schneider 2 cells after 1 hr by spectrofluorometry
Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Human proprotein convertase subtilisin/kexin type 7 (S8: Subtilisin)
Assay data:2 Active, 2 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of human PC7 expressed in drosophila schneider 2 cells using pyroGlu-Arg-Thr-Lys-Arg-AMC as substrate after 1 hr
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
Inhibition of recombinant type 8 subtilisin using Arg-Glu-(EDANS)- Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys-(DALBCYL)-Arg fluorogenic substrate at 0.001 ug/ml preincubated for 1 hr measured after 1 hr at 1 min interval by fluorescence assay
Assay data:3 Tested
Inhibition of recombinant type 8 subtilisin using Arg-Glu-(EDANS)- Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys-(DALBCYL)-Arg fluorogenic substrate at 0.01 ug/ml preincubated for 1 hr measured after 1 hr at 1 min interval by fluorescence assay
Inhibition of recombinant type 8 subtilisin using Arg-Glu-(EDANS)- Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys-(DALBCYL)-Arg fluorogenic substrate at 0.1 ug/ml preincubated for 1 hr measured after 1 hr at 1 min interval by fluorescence assay
Inhibition of recombinant type 8 subtilisin using Arg-Glu-(EDANS)- Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys-(DALBCYL)-Arg fluorogenic substrate at 1 ug/ml preincubated for 1 hr measured after 1 hr at 1 min interval by fluorescence assay
Inhibition of recombinant type 8 subtilisin using Arg-Glu-(EDANS)- Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys-(DALBCYL)-Arg fluorogenic substrate preincubated for 1 hr measured after 1 hr at 1 min interval by fluorescence assay
Assay data:2 Active, 1 Activity ≤ 1 µM, 7 Tested
Inhibition of human PC7 expressed in Drosophila schneider 2 cells by fluorescence assay
Assay data:3 Active, 1 Activity ≤ 1 µM, 5 Tested
Inhibition of human recombinant PC7 assessed as fluorescent Pyr-RTKR-AMC substrate cleavage
Assay data:6 Active, 4 Activity ≤ 1 µM, 6 Tested
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