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Binding affinity to CBP (unknown origin) assessed as dissociation constant
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Binding affinity to EP300 (unknown origin) assessed as dissociation constant
Binding affinity BRD4 (unknown origin) assessed as dissociation constant
Binding affinity BRD3 (unknown origin) assessed as dissociation constant
Binding affinity BRD2 (unknown origin) assessed as dissociation constant
In Vitro Bromodomain Inhibition Assay from US Patent US11365186: "Substituted benzimidazoles, their preparation and their use as pharmaceuticals"
Assay data:14 Active, 14 Activity ≤ 1 µM, 14 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
In Vitro Bromodomain Inhibition Assay from US Patent US10703740: "Substituted benzimidazoles, their preparation and their use as pharmaceuticals"
NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line
Assay data:3204 Active, 55031 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Depositor
NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line
Assay data:3125 Active, 54781 Tested
NCI human tumor cell line growth inhibition assay. Data for the TK-10 Renal cell line
Assay data:2149 Active, 54007 Tested
NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line
Assay data:3434 Active, 54892 Tested
NCI human tumor cell line growth inhibition assay. Data for the 786-0 Renal cell line
Assay data:3282 Active, 54398 Tested
NCI human tumor cell line growth inhibition assay. Data for the RXF 393 Renal cell line
Assay data:3628 Active, 49866 Tested
NCI human tumor cell line growth inhibition assay. Data for the CAKI-1 Renal cell line
Assay data:3482 Active, 52108 Tested
NCI human tumor cell line growth inhibition assay. Data for the A498 Renal cell line
Assay data:3670 Active, 48923 Tested
NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line
Assay data:5041 Active, 50324 Tested
NCI human tumor cell line growth inhibition assay. Data for the MOLT-4 Leukemia cell line
Assay data:4563 Active, 54231 Tested
NCI human tumor cell line growth inhibition assay. Data for the K-562 Leukemia cell line
Assay data:4962 Active, 53821 Tested
NCI human tumor cell line growth inhibition assay. Data for the CCRF-CEM Leukemia cell line
Assay data:5336 Active, 52551 Tested
NCI human tumor cell line growth inhibition assay. Data for the SR Leukemia cell line
Assay data:5652 Active, 45957 Tested
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