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Binding affinity to recombinant human IL-2 by SPR assay
Assay data:2 Active, 17 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Binding affinity to recombinant human IL-15 by SPR assay
Assay data:17 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of IL2R/IL2 interaction in human NK92 cells assessed as reduction IL2-induced STAT5 phosphorylation preincubated for 30 mins with IL2 followed by cell addition measured after 1 hr by AlphaScreen assay
SummaryPubMed Citation
Inhibition of IL15R/IL15 interaction in human NK92 cells assessed as reduction of IL15-induced STAT5 phosphorylation preincubated for 30 mins with IL15 followed by cell addition measured after 1 hr by AlphaScreen assay
Inhibition of recombinant human IL2R/IL2-induced mouse 32D-beta cell proliferation preincubated for 30 mins with protein followed by cell addition measured after 2.5 days by Alamar blue reduction assay
Assay data:27 Active, 9 Activity ≤ 1 µM, 51 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Inhibition of human IL-15Ralpha-sushi domain/human IL-15-induced mouse 32D-beta cell proliferation preincubated for 30 mins with protein followed by cell addition measured after 2.5 days by Alamar blue reduction assay
Assay data:27 Active, 3 Activity ≤ 1 µM, 51 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
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