BioAssays for PubChem Compound (Select 145925685) - PubChem BioAssay - NCBI

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Select item 19139171.

Selectivity interaction (KinomeScan (DiscoverX)) EUB0000305b PIK3CA

Source:: ChEMBL

Protein Target:: Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

Assay data:1 Tested

AID:: 1913917

Summary Related BioAssays by Target

Select item 19139162.

Selectivity interaction (KinomeScan (DiscoverX)) EUB0000305b SYK

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase SYK

Assay data:1 Tested

AID:: 1913916

Summary Related BioAssays by Target

Select item 19139153.

Selectivity interaction (GPCR panel (PDSP screen)) EUB0000305b TMEM97

Source:: ChEMBL

Protein Target:: Sigma intracellular receptor 2

Assay data:1 Active, 1 Tested

AID:: 1913915

Summary Compounds, Active Related BioAssays by Target

Select item 19139144.

Selectivity interaction (KinomeScan (DiscoverX)) EUB0000305b FLT3

Source:: ChEMBL

Protein Target:: Receptor-type tyrosine-protein kinase FLT3

Assay data:1 Tested

AID:: 1913914

Summary Related BioAssays by Target

Select item 19139135.

Selectivity interaction (NanoBRET assay (HEK293T cells)) EUB0000305b FLT3

Source:: ChEMBL

Protein Target:: Receptor-type tyrosine-protein kinase FLT3

Assay data:1 Tested

AID:: 1913913

Summary Related BioAssays by Target

Select item 19139126.

Selectivity interaction (Enzymatic assay) EUB0000305b FLT3

Source:: ChEMBL

Protein Target:: Receptor-type tyrosine-protein kinase FLT3

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1913912

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 19139117.

Selectivity interaction (NanoBRET assay (HEK293T cells)) EUB0000305b MAP2K5

Source:: ChEMBL

Protein Target:: Dual specificity mitogen-activated protein kinase kinase 5

Assay data:1 Tested

AID:: 1913911

Summary Related BioAssays by Target

Select item 19139108.

Selectivity interaction (KinomeScan (DiscoverX)) EUB0000305b MAP2K5

Source:: ChEMBL

Protein Target:: Dual specificity mitogen-activated protein kinase kinase 5

Assay data:1 Tested

AID:: 1913910

Summary Related BioAssays by Target

Select item 19139099.

Selectivity interaction (Enzymatic assay) EUB0000305b MAP2K5

Source:: ChEMBL

Protein Target:: Dual specificity mitogen-activated protein kinase kinase 5

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1913909

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 191390810.

Selectivity interaction (KinomeScan (DiscoverX)) EUB0000305b TAOK3

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase TAO3

Assay data:1 Tested

AID:: 1913908

Summary Related BioAssays by Target

Select item 191390711.

Selectivity interaction (NanoBRET assay (HEK293T cells)) EUB0000305b MAP3K19

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase kinase kinase 19

Assay data:1 Tested

AID:: 1913907

Summary Related BioAssays by Target

Select item 191390612.

Selectivity interaction (KinomeScan (DiscoverX)) EUB0000305b MAP3K19

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase kinase kinase 19

Assay data:1 Tested

AID:: 1913906

Summary Related BioAssays by Target

Select item 191390513.

Selectivity interaction (KinomeScan (DiscoverX, competition-binding assay)) EUB0000305b MAP3K19

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase kinase kinase 19

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1913905

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 191390414.

Selectivity interaction (Enzymatic assay) EUB0000305b ULK1

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase ULK1

Assay data:1 Active, 1 Tested

AID:: 1913904

Summary Compounds, Active Related BioAssays by Target

Select item 191390315.

Selectivity interaction (NanoBRET assay (HEK293T cells)) EUB0000305b STK17A

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase 17A

Assay data:1 Tested

AID:: 1913903

Summary Related BioAssays by Target

Select item 191390216.

Selectivity interaction (KinomeScan (DiscoverX)) EUB0000305b STK17A

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase 17A

Assay data:1 Tested

AID:: 1913902

Summary Related BioAssays by Target

Select item 191390117.

Selectivity interaction (Enzymatic assay (Eurofins)) EUB0000305b STK17A

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase 17A

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1913901

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 191390018.

Selectivity interaction (KinomeScan (DiscoverX, competition-binding assay)) EUB0000305b STK17A

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase 17A

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1913900

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 191389919.

Selectivity interaction (Enzymatic assay) EUB0000305b STK17A

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase 17A

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1913899

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 191389820.

Selectivity interaction (GPCR panel (PDSP screen)) EUB0000305b HTR2B

Source:: ChEMBL

Protein Target:: 5-hydroxytryptamine receptor 2B

Assay data:1 Active, 1 Tested

AID:: 1913898

Summary Compounds, Active Related BioAssays by Target

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Target

Proteins (2)
BioAssays with protein sequences specified as targets

BioActivity

Active Compounds (231)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (2)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (83)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Confirmatory (119)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations

Depositor Category

Literature Extraction (46)
BioAssays extracted from the literature
Other (582)
BioAssays deposited by other experimentalists

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BioAssays for PubChem Compound (Select 145925685) (628)
PubChem BioAssay
Taxonomy Links for Protein (Select 754158850) (1)
Taxonomy
inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform X3 [Homo sapi...
inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform X3 [Homo sapiens]
gi|2217272471|ref|XP_047290976.1|

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