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Inhibition of Akt phosphorylation in human HL60 cells after 24 to 48 hrs by Western blot analysis
Assay data:2 Tested
SummaryPubMed CitationRelated BioAssays by Target
Binding affinity to PHB2 in human HL60 cells assessed as upregulation of ERK phosphorylation at 0.1 uM after 24 hrs by Western blot analysis
Assay data:2 Active, 2 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Binding affinity to PHB2 in human HL60 cells assessed as LC3-2 accumulation at 0.1 to 10 uM after 24 hrs by Western blot analysis
Downregulation of PHB2 in human HL60 cells at 0.1 to 10 uM after 24 hrs by Western blot analysis
Downregulation of PHB1 in human HL60 cells at 0.1 to 10 uM after 24 hrs by Western blot analysis
Induction of apoptosis in human MM162 cells at 1 to 10 uM after 48 hrs by Annexin V-PE/7-AAD staining based flow cytometry
SummaryCompounds, ActivePubMed Citation
Induction of apoptosis in human MM043 cells at 1 to 10 uM after 48 hrs by Annexin V-PE/7-AAD staining based flow cytometry
Induction of apoptosis in human HBL cells at 1 to 10 uM after 48 hrs by Annexin V-PE/7-AAD staining based flow cytometry
Inhibition of cell proliferation in human KB cells after 72 hrs by MTS assay
Assay data:3 Tested
SummaryPubMed Citation
Inhibition of cell proliferation in human HL60 cells after 72 hrs by MTS assay
Inhibition of Akt phosphorylation in human MM162 cells at 0.1 to 10 uM after 24 hrs by Western blot analysis
Assay data:1 Active, 1 Tested
Downregulation of PHB2 in human MM162 cells at 0.1 to 10 uM after 24 hrs by Western blot analysis
Downregulation of PHB1 in human MM162 cells at 0.1 to 10 uM after 24 hrs by Western blot analysis
Inhibition of Akt phosphorylation in human MM043 cells at 0.1 to 10 uM after 24 hrs by Western blot analysis
Downregulation of PHB2 in human MM043 cells at 0.1 to 10 uM after 24 hrs by Western blot analysis
Downregulation of PHB1 in human MM043 cells at 0.1 to 10 uM after 24 hrs by Western blot analysis
Inhibition of Akt phosphorylation in human HBL cells at 0.1 to 10 uM after 24 to 48 hrs by Western blot analysis
Downregulation of PHB2 in human HBL cells at 0.1 to 10 uM after 24 to 48 hrs by Western blot analysis
Binding affinity to PHB2 in human HBL cells assessed as feedback mechanism based inhibition of ERK phosphorylation at 0.1 to 10 uM after 48 hrs by Western blot analysis
Binding affinity to PHB2 in human HBL cells assessed as upregulation of ERK phosphorylation at 0.1 to 10 uM after 24 hrs by Western blot analysis
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