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Antiproliferative activity against human 22Rv1 cells assessed as inhibition of cell growth incubated for 96 to 120 hrs by celltiter glo assay
Assay data:2 Active, 1 Activity ≤ 1 µM, 26 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Antiproliferative activity against human 22Rv1 cells assessed as inhibition of cell growth at 10 uM incubated for 96 to 120 hrs by celltiter glo assay relative to control
Assay data:26 Tested
SummaryPubMed Citation
Antiproliferative activity against human MV4-11 cells assessed as inhibition of cell growth incubated for 96 to 120 hrs by celltiter glo assay
Assay data:8 Active, 1 Activity ≤ 1 µM, 26 Tested
Antiproliferative activity against human MV4-11 cells assessed as inhibition of cell growth at 10 uM incubated for 96 to 120 hrs by celltiter glo assay relative to control
Inhibition of BRD4-BD1 (unknown origin) using C-terminal biotinylated tetra-acetylated histone H4 peptide as substrate incubated for 2.5 hrs by alphascreen assay
Assay data:14 Active, 1 Activity ≤ 1 µM, 26 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of BRD4-BD1 (unknown origin) using C-terminal biotinylated tetra-acetylated histone H4 peptide as substrate at 20 uM incubated for 2.5 hrs by alphascreen assay relative to control
SummaryPubMed CitationRelated BioAssays by Target
Binding affinity to BRD4-BD1 (unknown origin) assessed as change in melting temperature at 200 uM incubated for 30 to 60 mins by SYPRO orange dye based thermal shift assay
NCI human tumor cell line growth inhibition assay. Data for the KM12 Non-Small Cell Lung cell line, single concentration
Assay data:3444 Active, 76734 Tested
SummaryCompounds, ActiveRelated BioAssays by Depositor
NCI human tumor cell line growth inhibition assay. Data for the HCC-2998 Non-Small Cell Lung cell line, single concentration
Assay data:3073 Active, 74254 Tested
NCI human tumor cell line growth inhibition assay. Data for the HCT-116 Non-Small Cell Lung cell line, single concentration
Assay data:5131 Active, 77082 Tested
NCI human tumor cell line growth inhibition assay. Data for the MCF7 Non-Small Cell Lung cell line, single concentration
Assay data:4318 Active, 77515 Tested
NCI human tumor cell line growth inhibition assay. Data for the SW-620 Non-Small Cell Lung cell line, single concentration
Assay data:3653 Active, 76840 Tested
NCI human tumor cell line growth inhibition assay. Data for the MDA-MB-435 Non-Small Cell Lung cell line, single concentration
Assay data:5608 Active, 76570 Tested
NCI human tumor cell line growth inhibition assay. Data for the BT-549 Non-Small Cell Lung cell line, single concentration
Assay data:2768 Active, 73031 Tested
NCI human tumor cell line growth inhibition assay. Data for the T-47D Non-Small Cell Lung cell line, single concentration
Assay data:3353 Active, 74196 Tested
NCI human tumor cell line growth inhibition assay. Data for the NCI/ADR-RES Non-Small Cell Lung cell line, single concentration
Assay data:3002 Active, 76488 Tested
NCI human tumor cell line growth inhibition assay. Data for the MDA-MB-231/ATCC Non-Small Cell Lung cell line, single concentration
Assay data:3404 Active, 76205 Tested
NCI human tumor cell line growth inhibition assay. Data for the HS 578T Non-Small Cell Lung cell line, single concentration
Assay data:2612 Active, 73180 Tested
NCI human tumor cell line growth inhibition assay. Data for the OVCAR-3 Non-Small Cell Lung cell line, single concentration
Assay data:5012 Active, 76370 Tested
NCI human tumor cell line growth inhibition assay. Data for the IGROV1 Non-Small Cell Lung cell line, single concentration
Assay data:3242 Active, 74206 Tested
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