Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Binding affinity to duplex DNA (unknown origin) using fluorescent tagged F10T model assessed as stabilization by measuring change in melting temperature at 2 uM by fluorescence based analysis
Assay data:5 Tested
SummaryPubMed Citation
Binding affinity to c-MYC G4-quadruplex DNA (unknown origin) using fluorescent tagged FPu18T model assessed as stabilization by measuring change in melting temperature at 2 uM by fluorescence based analysis
Antitumor activity against human H22 cells xenografted in ICR mouse assessed as inhibition of tumor growth at 20 mg/kg, iv administered for 21 days and measured every 2 days relative to control
Assay data:3 Tested
Antiproliferative activity against human LX2 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Assay data:1 Active, 2 Tested
SummaryCompounds, ActivePubMed Citation
Antiproliferative activity against cisplatin-resistant human HepG2 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Antiproliferative activity against human Hep3B cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Antiproliferative activity against human Huh-7 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Antiproliferative activity against human SK-HEP1 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Antiproliferative activity against human HepG2 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Assay data:15 Active, 1 Activity ≤ 1 µM, 16 Tested
Toxicity in Sprague-Dawley rat assessed as LOAEL by po administrated gestational day upto 20 days
Assay data:1 Tested
Toxicity in Sprague-Dawley rat assessed as NOAEL by po administrated gestational day upto 20 days
Induction of DNA damage in human HaCaT cells assessed as fold change at 50 uM in presence of UV radiation by comet assay
Cytotoxicity against human HaCaT cells assessed as decrease in cell viability at 50 uM incubated for 1 hr in presence of UV radiation by CellTiter-96 assay
Oral bioavailability in Wistar rat at 100 mg/kg by UPLC-MS/MS analysis
Binding affinity to PPARalpha (unknown origin)
Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Agonist activity at PPARalpha (unknown origin) relative to control
Assay data:2 Tested
SummaryPubMed CitationRelated BioAssays by Target
Agonist activity at PPARdelta (unknown origin)
Assay data:1 Active, 1 Activity ≤ 1 µM, 4 Tested
Agonist activity at PPARalpha (unknown origin)
Assay data:3 Active, 2 Activity ≤ 1 µM, 4 Tested
Inhibition of AChE (unknown origin)
Assay data:49 Active, 6 Activity ≤ 1 nM, 34 Activity ≤ 1 µM, 58 Tested
Antiproliferative activity against human PC-3 cells
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on