BioAssays for PubChem Compound (Select 24794418) - PubChem BioAssay - NCBI

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Select item 19189691.

Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress

Source:: ICCB-Longwood Screening Facility, Harvard Medical School

Assay data:281 Active, 189401 Tested

AID:: 1918969

Summary Compounds, Active

Select item 19135312.

Selectivity interaction (Enzymatic assay) EUB0000624a PRKACA

Source:: ChEMBL

Protein Target:: cAMP-dependent protein kinase catalytic subunit alpha

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1913531

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 19135303.

Selectivity interaction (Enzymatic assay) EUB0000624a KDR

Source:: ChEMBL

Protein Target:: Vascular endothelial growth factor receptor 2

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1913530

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 19135294.

Selectivity interaction (Ambit kinome screening platform (Ambit phage-based competition binding assay)) EUB0000624a KDR

Source:: ChEMBL

Protein Target:: Vascular endothelial growth factor receptor 2

Assay data:1 Tested

AID:: 1913529

Summary Related BioAssays by Target

Select item 19135285.

Selectivity interaction (Ambit kinome screening platform (Ambit phage-based competition binding assay)) EUB0000624a FLT4

Source:: ChEMBL

Protein Target:: Vascular endothelial growth factor receptor 3

Assay data:1 Tested

AID:: 1913528

Summary Related BioAssays by Target

Select item 19135276.

Selectivity interaction (Ambit kinome screening platform (Ambit phage-based competition binding assay)) EUB0000624a NTRK3

Source:: ChEMBL

Protein Target:: NT-3 growth factor receptor

Assay data:1 Tested

AID:: 1913527

Summary Related BioAssays by Target

Select item 19135267.

Selectivity interaction (Enzymatic assay) EUB0000624a NTRK2

Source:: ChEMBL

Protein Target:: BDNF/NT-3 growth factors receptor

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1913526

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 19135258.

Selectivity interaction (Ambit kinome screening platform (Ambit phage-based competition binding assay)) EUB0000624a NTRK2

Source:: ChEMBL

Protein Target:: BDNF/NT-3 growth factors receptor

Assay data:1 Tested

AID:: 1913525

Summary Related BioAssays by Target

Select item 19135249.

Selectivity interaction (Enzymatic assay) EUB0000624a NTRK1

Source:: ChEMBL

Protein Target:: High affinity nerve growth factor receptor

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1913524

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 191352310.

Selectivity interaction (Ambit kinome screening platform (Ambit phage-based competition binding assay)) EUB0000624a NTRK1

Source:: ChEMBL

Protein Target:: High affinity nerve growth factor receptor

Assay data:1 Tested

AID:: 1913523

Summary Related BioAssays by Target

Select item 191352211.

Selectivity interaction (Ambit kinome screening platform (Ambit phage-based competition binding assay)) EUB0000624a TEK

Source:: ChEMBL

Protein Target:: Angiopoietin-1 receptor

Assay data:1 Tested

AID:: 1913522

Summary Related BioAssays by Target

Select item 191352112.

Selectivity interaction (Enzymatic assay) EUB0000624a BTK

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase BTK

Assay data:1 Tested

AID:: 1913521

Summary Related BioAssays by Target

Select item 191352013.

Selectivity interaction (Ambit kinome screening platform (Ambit phage-based competition binding assay)) EUB0000624a FRK

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase FRK

Assay data:1 Tested

AID:: 1913520

Summary Related BioAssays by Target

Select item 191351914.

Selectivity interaction (Enzymatic assay) EUB0000624a LCK

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase Lck

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1913519

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 191351815.

Selectivity interaction (Ambit kinome screening platform (Ambit phage-based competition binding assay)) EUB0000624a LCK

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase Lck

Assay data:1 Tested

AID:: 1913518

Summary Related BioAssays by Target

Select item 191351716.

Selectivity interaction (Ambit kinome screening platform (Ambit phage-based competition binding assay)) EUB0000624a BLK

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase Blk

Assay data:1 Tested

AID:: 1913517

Summary Related BioAssays by Target

Select item 191351617.

Selectivity interaction (Ambit kinome screening platform (Ambit phage-based competition binding assay)) EUB0000624a PDGFRB

Source:: ChEMBL

Protein Target:: Platelet-derived growth factor receptor beta

Assay data:1 Tested

AID:: 1913516

Summary Related BioAssays by Target

Select item 191351518.

Selectivity interaction (Ambit kinome screening platform (Ambit phage-based competition binding assay)) EUB0000624a PDGFRA

Source:: ChEMBL

Protein Target:: Platelet-derived growth factor receptor alpha

Assay data:1 Tested

AID:: 1913515

Summary Related BioAssays by Target

Select item 191351419.

Selectivity interaction (Ambit kinome screening platform (Ambit phage-based competition binding assay)) EUB0000624a KIT

Source:: ChEMBL

Protein Target:: Mast/stem cell growth factor receptor Kit

Assay data:1 Tested

AID:: 1913514

Summary Related BioAssays by Target

Select item 191351320.

Selectivity interaction (Enzymatic assay) EUB0000624a FLT3

Source:: ChEMBL

Protein Target:: Receptor-type tyrosine-protein kinase FLT3

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1913513

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

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Proteins (35)
BioAssays with protein sequences specified as targets

BioActivity

Active Compounds (589)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (82)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (396)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Confirmatory (569)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (66)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose

Assay Project (32)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (229)
BioAssays extracted from the literature
NIH MLP (80)
BioAssays deposited by the NIH Molecular Libraries Program
Other (525)
BioAssays deposited by other experimentalists

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