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NOS Enzyme Inhibition Assay from Article 10.1038/nchembio.115: "Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase."
Assay data:15 Active, 14 Activity ≤ 1 µM, 15 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Binding affinity to mouse iNOSox delta65 (residues 66-498)
Assay data:11 Active, 11 Tested
SummaryCompounds, ActivePubMed Citation
Selectivity ratio of IC50 for human iNOS over IC50 for human nNOS
Assay data:12 Tested
SummaryPubMed Citation
Selectivity ratio of IC50 for human iNOS over IC50 for human eNOS
Inhibition of human nNOS
Assay data:11 Active, 8 Activity ≤ 1 µM, 15 Tested
Inhibition of human eNOS
Assay data:7 Active, 4 Activity ≤ 1 µM, 15 Tested
Inhibition of human iNOS
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