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Inhibition of human topoisomerase 1
Assay data:2 Active, 2 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Induction of apoptosis in human HT-29 cells assessed as necrotic cells at 0.9 uM incubated for 24 hrs by Annexin-V/PI staining based flow cytometric analysis (Rvb = 0.01%)
Assay data:3 Tested
SummaryPubMed Citation
Induction of apoptosis in human HT-29 cells assessed as late apoptotic cells at 0.9 uM incubated for 24 hrs by Annexin-V/PI staining based flow cytometric analysis (Rvb = 4.50%)
Induction of apoptosis in human HT-29 cells assessed as early apoptotic cells at 0.9 uM incubated for 24 hrs by Annexin-V/PI staining based flow cytometric analysis (Rvb = 2.59%)
Induction of apoptosis in human HT-29 cells assessed as viable cells at 0.9 uM incubated for 24 hrs by Annexin-V/PI staining based flow cytometric analysis (Rvb = 92.90%)
Induction of apoptosis in human HGC-27 cells assessed as necrotic cells at 2.7 uM incubated for 24 hrs by Annexin-V/PI staining based flow cytometric analysis (Rvb = 0.15%)
Induction of apoptosis in human HGC-27 cells assessed as late apoptotic cells at 2.7 uM incubated for 24 hrs by Annexin-V/PI staining based flow cytometric analysis (Rvb = 9.22%)
Induction of apoptosis in human HGC-27 cells assessed as early apoptotic cells at 2.7 uM incubated for 24 hrs by Annexin-V/PI staining based flow cytometric analysis (Rvb = 0.09%)
Induction of apoptosis in human HGC-27 cells assessed as viable cells at 2.7 uM incubated for 24 hrs by Annexin-V/PI staining based flow cytometric analysis (Rvb = 90.54%)
Cell cycle arrest in human HGC-27 cells assessed as accumulation of cells at S phase at 0.1 to 0.9 microM incubated for 24 hrs by flow cytometric analysis relative to control
Assay data:1 Tested
Cell cycle arrest in human HT-29 cells assessed as accumulation of cells at G2/M phase at 0.1 to 0.9 microM incubated for 24 hrs by flow cytometric analysis relative to control
Assay data:2 Tested
Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Assay data:7 Active, 1 Activity ≤ 1 µM, 22 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Antiproliferative activity against human A549 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Assay data:3 Active, 22 Tested
SummaryCompounds, ActivePubMed Citation
Antiproliferative activity against human HepG2 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Assay data:1 Active, 22 Tested
Antiproliferative activity against human HT-29 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Assay data:10 Active, 22 Tested
Antiproliferative activity against human HGC-27 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Assay data:13 Active, 3 Activity ≤ 1 µM, 22 Tested
Antiproliferative activity against human GES1 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Assay data:11 Active, 22 Tested
Anticancer human tumor SW1271 cell line growth inhibition [AhR]
Assay data:15 Active, 103 Tested
SummaryCompounds, ActiveRelated BioAssays by Depositor
Anticancer human tumor NCI-H196 cell line growth inhibition [AhR]
Assay data:24 Active, 103 Tested
Anticancer human tumor OVCAR-5 cell line growth inhibition [AhR]
Assay data:37 Active, 103 Tested
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