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Aqueous solubility of the compound
Assay data:6 Tested
SummaryPubMed Citation
Inhibition of mTORC2 in human RD cells assessed as reduction in Akt phosphorylation at Ser473 site at 20 uM incubated for 2 hrs in presence of insulin by Western blot analysis
Assay data:16 Active, 19 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of mTORC1 in human RD cells assessed as reduction in P70S6K1 phosphorylation at Thr 389 site at 20 uM incubated for 2 hrs in presence of insulin by Western blot analysis
Assay data:19 Active, 22 Tested
Cytotoxicity against human RD cells incubated for 4 days by CellTiter-Glo luminescence assay
Assay data:21 Active, 14 Activity ≤ 1 µM, 31 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Antiviral activity against Enterovirus A71 infected in human RD cells assessed as reduction in virus-induced cell death incubated for 4 days by CellTiter-Glo luminescence assay
Assay data:20 Active, 13 Activity ≤ 1 µM, 31 Tested
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