BioAssays for PubChem Compound (Select 71731823) - PubChem BioAssay - NCBI

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Select item 19618781.

Binding affinity towards human HRH3 in an in vitro assay with cellular components measured by scintillation counting

Source:: ChEMBL

Protein Target:: Histamine H3 receptor

Assay data:41 Active, 7 Activity ≤ 1 µM, 993 Tested

AID:: 1961878

Summary Related BioAssays by Target

Select item 19618712.

Antagonist activity at human TBXA2R in an in vitro cell-based assay measured by fluorescence spectroscopy

Source:: ChEMBL

Protein Target:: Thromboxane A2 receptor

Assay data:8 Active, 1 Activity ≤ 1 µM, 71 Tested

AID:: 1961871

Summary Related BioAssays by Target

Select item 19618703.

Compound was evaluated for inhibition of human KDR in an in vitro cell free assay measured by time-resolved fluorescence resonance energy transfer method

Source:: ChEMBL

Protein Target:: Vascular endothelial growth factor receptor 2

Assay data:12 Active, 3 Activity ≤ 1 nM, 7 Activity ≤ 1 µM, 101 Tested

AID:: 1961870

Summary Related BioAssays by Target

Select item 19618694.

Compound was evaluated for inhibition of human ACHE in an vitro cell free assay measured by absorbance method

Source:: ChEMBL

Protein Target:: Acetylcholinesterase

Assay data:10 Active, 5 Activity ≤ 1 µM, 73 Tested

AID:: 1961869

Summary Related BioAssays by Target

Select item 19618585.

Antagonist activity at human ADRA1A in an in vitro cell-based assay measured by fluorescence spectroscopy

Source:: ChEMBL

Protein Target:: Alpha-1A adrenergic receptor

Assay data:117 Active, 53 Activity ≤ 1 µM, 881 Tested

AID:: 1961858

Summary Related BioAssays by Target

Select item 19618566.

Binding affinity towards human DRD3 in an in vitro assay with cellular components measured by scintillation counting

Source:: ChEMBL

Protein Target:: D(3) dopamine receptor

Assay data:176 Active, 1 Activity ≤ 1 nM, 87 Activity ≤ 1 µM, 1215 Tested

AID:: 1961856

Summary Related BioAssays by Target

Select item 19618557.

Compound was evaluated for inhibition of human PDE3A in an in vitro cell free assay measured by time-resolved fluorescence resonance energy transfer method

Source:: ChEMBL

Protein Target:: cGMP-inhibited 3',5'-cyclic phosphodiesterase A

Assay data:49 Active, 5 Activity ≤ 1 µM, 1243 Tested

AID:: 1961855

Summary Related BioAssays by Target

Select item 19618528.

Compound was evaluated for inhibition of human MAOA in an in vitro cell free assay measured by fluorescence spectroscopy

Source:: ChEMBL

Protein Target:: Amine oxidase [flavin-containing] A

Assay data:28 Active, 4 Activity ≤ 1 µM, 1218 Tested

AID:: 1961852

Summary Related BioAssays by Target

Select item 19618519.

Binding affinity towards human OPRM1 in an in vitro assay with cellular components measured by scintillation counting

Source:: ChEMBL

Protein Target:: Mu-type opioid receptor

Assay data:60 Active, 9 Activity ≤ 1 µM, 766 Tested

AID:: 1961851

Summary Related BioAssays by Target

Select item 196184910.

Binding affinity towards human SLC6A4 in an in vitro assay with cellular components measured by scintillation counting

Source:: ChEMBL

Protein Target:: Sodium-dependent serotonin transporter

Assay data:148 Active, 75 Activity ≤ 1 µM, 1194 Tested

AID:: 1961849

Summary Related BioAssays by Target

Select item 196184811.

Binding affinity towards human SLC6A2 in an in vitro assay with cellular components measured by scintillation counting

Source:: ChEMBL

Protein Target:: Sodium-dependent noradrenaline transporter

Assay data:123 Active, 40 Activity ≤ 1 µM, 1197 Tested

AID:: 1961848

Summary Related BioAssays by Target

Select item 196184712.

Binding affinity towards human SLC6A3 in an in vitro assay with cellular components measured by scintillation counting

Source:: ChEMBL

Protein Target:: Sodium-dependent dopamine transporter

Assay data:119 Active, 21 Activity ≤ 1 µM, 1213 Tested

AID:: 1961847

Summary Related BioAssays by Target

Select item 196184313.

Agonist activity at human TBXA2R in an in vitro cell free assay (NIBR assay) measured by fluorescent imaging plate reader

Source:: ChEMBL

Protein Target:: Thromboxane A2 receptor

Assay data:71 Tested

AID:: 1961843

Summary Related BioAssays by Target

Select item 196183714.

Binding affinity towards human SLC29A1 in an in vitro assay with cellular components measured by scintillation proximity assay

Source:: ChEMBL

Protein Target:: Equilibrative nucleoside transporter 1

Assay data:20 Active, 4 Activity ≤ 1 µM, 1115 Tested

AID:: 1961837

Summary Related BioAssays by Target

Select item 196183515.

Compound was evaluated for inhibition of human SCN5A in an in vitro cell-based assay measured by IonWorks automated patch clamp

Source:: ChEMBL

Protein Target:: Sodium channel protein type 5 subunit alpha

Assay data:37 Active, 5 Activity ≤ 1 µM, 230 Tested

AID:: 1961835

Summary Related BioAssays by Target

Select item 196182716.

Compound was evaluated for inhibition of human PTGS2 in an in vitro cell free assay measured by fluorescence spectroscopy

Source:: ChEMBL

Protein Target:: Prostaglandin G/H synthase 2

Assay data:79 Active, 12 Activity ≤ 1 µM, 1183 Tested

AID:: 1961827

Summary Related BioAssays by Target

Select item 196182517.

Compound was evaluated for inhibition of rat Ptgs1 in an in vitro cell free assay measured by fluorescence spectroscopy

Source:: ChEMBL

Protein Target:: Prostaglandin G/H synthase 1

Assay data:74 Active, 33 Activity ≤ 1 µM, 1201 Tested

AID:: 1961825

Summary Related BioAssays by Target

Select item 196182418.

Antagonist activity at human PPARG in an in vitro cell free assay measured by time-resolved fluorescence resonance energy transfer method

Source:: ChEMBL

Protein Target:: Peroxisome proliferator-activated receptor gamma

Assay data:10 Active, 3 Activity ≤ 1 µM, 238 Tested

AID:: 1961824

Summary Related BioAssays by Target

Select item 196182319.

Agonist activity at human PPARG in an in vitro cell free assay measured by time-resolved fluorescence resonance energy transfer method

Source:: ChEMBL

Protein Target:: Peroxisome proliferator-activated receptor gamma

Assay data:4 Active, 5 Activity ≤ 1 µM, 238 Tested

AID:: 1961823

Summary Related BioAssays by Target

Select item 196181820.

Antagonist activity at human PGR in an in vitro cell free assay measured by time-resolved fluorescence resonance energy transfer method

Source:: ChEMBL

Protein Target:: Progesterone receptor

Assay data:29 Active, 4 Activity ≤ 1 µM, 850 Tested

AID:: 1961818

Summary Related BioAssays by Target

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Target

Proteins (17)
BioAssays with protein sequences specified as targets

BioActivity

Active Compounds (237)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (37)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (98)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Confirmatory (245)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (57)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose

Assay Project (2)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (191)
BioAssays extracted from the literature
NIH MLP (21)
BioAssays deposited by the NIH Molecular Libraries Program
Other (188)
BioAssays deposited by other experimentalists

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