Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Navigating the Kinome
Assay data:1497 Active, 1497 Tested
SummaryCompounds, ActivePubMed Citation
Efficacy in serum sICAM-1 at 3 mg/kg of oral dosing in an inhaled allergen-induced cell influx in 7 mice.
Assay data:1 Tested
SummaryPubMed Citation
Efficacy in serum sICAM-1 at 30 mg/kg of oral dosing in an inhaled allergen-induced cell influx in 6 mice.
Efficacy in serum sICAM-1 at 0.3 mg/kg of oral dosing in an inhaled allergen-induced cell influx in 7 mice.
Efficacy in lavage cells at 3 mg/kg of oral dosing in an inhaled allergen-induced cell influx in 7 mice.
Efficacy in lavage cells at 30 mg/kg of oral dosing in an inhaled allergen-induced cell influx in 6 mice.
Efficacy in lavage cells at 0.3 mg/kg of oral dosing in an inhaled allergen-induced cell influx in 7 mice.
Efficacy in lBAL sICAM-1 at 3 mg/kg of oral dosing in an inhaled allergen-induced cell influx in 7 mice.
Efficacy in lBAL sICAM-1 at 30 mg/kg of oral dosing in an inhaled allergen-induced cell influx in 6 mice.
Efficacy in lBAL sICAM-1 at 0.3 mg/kg of oral dosing in an inhaled allergen-induced cell influx in 7 mice.
% Efficacy in neutrophils at 3 mg/kg of oral dosing in an inhaled allergen-induced cell influx in 7 mice.
% Efficacy in neutrophils at 30 mg/kg of oral dosing in an inhaled allergen-induced cell influx in 6 mice.
% Efficacy in neutrophils at 0.3 mg/kg of oral dosing in an inhaled allergen-induced cell influx in 7 mice.
% Efficacy in eosinophils at 3 mg/kg of oral dosing in an inhaled allergen-induced cell influx in 7 mice.
% Efficacy in eosinophils at 30 mg/kg of oral dosing in an inhaled allergen-induced cell influx in 6 mice.
% Efficacy in eosinophils at 0.3 mg/kg of oral dosing in an inhaled allergen-induced cell influx in 7 mice.
In vitro inhibitory potency compared to TNF-alpha induced VCAM-1 in human endothelial cells (ELISA assay)
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
In vitro inhibitory potency compared to PMA induced VCAM-1 in human endothelial cells (ELISA assay)
In vitro inhibitory potency compared to IL1-beta induced VCAM-1 in human endothelial cells (ELISA assay)
Inhibition of VCAM-1 in human endothelial cells
Assay data:26 Active, 79 Activity ≤ 1 µM, 85 Tested
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on