BioAssays, Active for PubChem Compound (Select 145925685) - PubChem BioAssay - NCBI

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Select item 19139151.

Selectivity interaction (GPCR panel (PDSP screen)) EUB0000305b TMEM97

Source:: ChEMBL

Protein Target:: Sigma intracellular receptor 2

Assay data:1 Active, 1 Tested

AID:: 1913915

Summary Compounds, Active Related BioAssays by Target

Select item 19139122.

Selectivity interaction (Enzymatic assay) EUB0000305b FLT3

Source:: ChEMBL

Protein Target:: Receptor-type tyrosine-protein kinase FLT3

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1913912

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 19139093.

Selectivity interaction (Enzymatic assay) EUB0000305b MAP2K5

Source:: ChEMBL

Protein Target:: Dual specificity mitogen-activated protein kinase kinase 5

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1913909

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 19139054.

Selectivity interaction (KinomeScan (DiscoverX, competition-binding assay)) EUB0000305b MAP3K19

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase kinase kinase 19

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1913905

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 19139045.

Selectivity interaction (Enzymatic assay) EUB0000305b ULK1

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase ULK1

Assay data:1 Active, 1 Tested

AID:: 1913904

Summary Compounds, Active Related BioAssays by Target

Select item 19139016.

Selectivity interaction (Enzymatic assay (Eurofins)) EUB0000305b STK17A

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase 17A

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1913901

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 19139007.

Selectivity interaction (KinomeScan (DiscoverX, competition-binding assay)) EUB0000305b STK17A

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase 17A

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1913900

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 19138998.

Selectivity interaction (Enzymatic assay) EUB0000305b STK17A

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase 17A

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1913899

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 19138989.

Selectivity interaction (GPCR panel (PDSP screen)) EUB0000305b HTR2B

Source:: ChEMBL

Protein Target:: 5-hydroxytryptamine receptor 2B

Assay data:1 Active, 1 Tested

AID:: 1913898

Summary Compounds, Active Related BioAssays by Target

Select item 191389710.

Selectivity interaction (Enzymatic assay) EUB0000305b RPS6KA6

Source:: ChEMBL

Protein Target:: Ribosomal protein S6 kinase alpha-6

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1913897

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 191315911.

Affinity Biochemical interaction (TR-FRET-based kinase activity inhibition assay (1 M ATP)) EUB0000305b TBK1

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase TBK1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1913159

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 191315812.

Affinity Biochemical interaction (TR-FRET-based kinase activity inhibition assay (1 M ATP)) EUB0000305b IKBKE

Source:: ChEMBL

Protein Target:: Inhibitor of nuclear factor kappa-B kinase subunit epsilon

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1913158

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 191290113.

Affinity On-target Cellular interaction (NanoBRET assay (HEK293T cells)) EUB0000305b TBK1

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase TBK1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1912901

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 191290014.

Affinity On-target Cellular interaction (NanoBRET assay (HEK293T cells)) EUB0000305b IKBKE

Source:: ChEMBL

Protein Target:: Inhibitor of nuclear factor kappa-B kinase subunit epsilon

Assay data:1 Active, 1 Tested

AID:: 1912900

Summary Compounds, Active Related BioAssays by Target

Select item 191274215.

Affinity Phenotypic Cellular interaction (pIRF3 cell-based mechanistic assay in MDA-MB231 cells) EUB0000305b TBK1

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase TBK1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1912742

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 191274116.

Affinity Phenotypic Cellular interaction (pIRF3 cell-based mechanistic assay in MDA-MB231 cells) EUB0000305b IKBKE

Source:: ChEMBL

Protein Target:: Inhibitor of nuclear factor kappa-B kinase subunit epsilon

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1912741

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 179256517.

NanoBRET with IKBKE

Source:: ChEMBL

Protein Target:: Inhibitor of nuclear factor kappa-B kinase subunit epsilon

Assay data:1 Active, 1 Tested

AID:: 1792565

Summary Compounds, Active Related BioAssays by Target

Select item 179256418.

NanoBRET with TBK1

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase TBK1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1792564

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 179256319.

Biochemical assay (low ATP) with IKBKE

Source:: ChEMBL

Protein Target:: Inhibitor of nuclear factor kappa-B kinase subunit epsilon

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1792563

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 179256220.

Biochemical assay (high ATP) with TBK1

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase TBK1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1792562

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

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BioActivity

Active Compounds (38)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (2)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (27)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Confirmatory (33)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations

Depositor Category

Literature Extraction (13)
BioAssays extracted from the literature
Other (25)
BioAssays deposited by other experimentalists

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BioAssays, Active for PubChem Compound (Select 145925685) (38)
PubChem BioAssay
BioAssays, Active for PubChem Compound (Select 10077147) (435)
PubChem BioAssay
freshwater sediment metagenome
freshwater sediment metagenome
Multi-omics of the nitrate-reducing iron(II)-oxidizing culture BP

BioProject
BioProject Links for BioSample (Select 17387790) (1)
BioProject
Allocoleopsis franciscana PCC 7113, complete sequence
Allocoleopsis franciscana PCC 7113, complete sequence
gi|428308377|ref|NC_019738.1|

Nucleotide

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