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qHTS assay for MDR1-selective chemotherapeutics: Primary screen using the drug-selected MDR subline cells KB-V1
Assay data:13449 Active, 399619 Tested
SummaryCompounds, ActiveRelated BioAssays by Depositor
TRFRET-based cell-based high throughput confirmation assay to identify inhibitors of cell surface Prion Protein (PRPC)
Assay data:949 Active, 1465 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Fluorescence polarization-based biochemical high throughput confirmation assay to identify inhibitors of alpha/beta hydrolase domain containing 4 (ABHD4).
Assay data:1002 Active, 1829 Tested
TRFRET-based cell-based primary high throughput screening assay to identify inhibitors of cell surface Prion Protein (PRPC)
Assay data:1597 Active, 370276 Tested
Fluorescence polarization-based biochemical high throughput primary assay to identify inhibitors of alpha/beta hydrolase domain containing 4 (ABHD4).
Assay data:2015 Active, 370276 Tested
qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT
Assay data:49946 Active, 2 Activity ≤ 1 nM, 3516 Activity ≤ 1 µM, 424035 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT
Assay data:64212 Active, 1 Activity ≤ 1 nM, 3794 Activity ≤ 1 µM, 424003 Tested
qHTS Assay for Inhibitors of Hepatitis C Virus (HCV)
Assay data:11664 Active, 1 Activity ≤ 1 nM, 2851 Activity ≤ 1 µM, 343600 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Same Project
qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode)
Assay data:6432 Active, 3053 Activity ≤ 1 µM, 408352 Tested
A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells.
Assay data:6247 Active, 4 Activity ≤ 1 nM, 12419 Activity ≤ 1 µM, 344074 Tested
A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells.
Assay data:9908 Active, 6263 Activity ≤ 1 µM, 345034 Tested
qHTS for inhibitors of binding or entry into cells for Marburg Virus
Assay data:5375 Active, 30 Activity ≤ 1 nM, 10501 Activity ≤ 1 µM, 301745 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same Project
qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1
Assay data:7656 Active, 3127 Activity ≤ 1 µM, 330279 Tested
Specificity screen assay against KCNQ2 for identification of compounds that potentiate KCNQ1 potassium channels
Assay data:836 Active, 2435 Tested
Validation assay for identification of compounds that potentiate KCNQ1 potassium channels
Assay data:1024 Active, 2435 Tested
Counter screen assay of the parental CHO cells for identification of compounds that potentiate KCNQ1 potassium channels
Assay data:757 Active, 2435 Tested
qHTS for inhibitors of ROR gamma transcriptional activity
Assay data:16824 Active, 4 Activity ≤ 1 nM, 4465 Activity ≤ 1 µM, 309031 Tested
VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity
Assay data:10662 Active, 5 Activity ≤ 1 nM, 1977 Activity ≤ 1 µM, 307648 Tested
Primary cell-based high-throughput screening assay for identification of compounds that potentiate/activate KCNQ1 potassium channels
Assay data:1082 Active, 305679 Tested
Confirmatory screen for compounds that potentiate KCNQ2 potassium channels
Assay data:804 Active, 1189 Tested
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
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