BioAssays, Active for PubChem Compound (Select 21591148) - PubChem BioAssay - NCBI

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Items: 10

Select item 17586391.

Anti-austerity activity against human KLM-1 cells assessed as cell killing in nutrient deprived medium

Source:: ChEMBL

Assay data:4 Active, 3 Activity ≤ 1 µM, 5 Tested

AID:: 1758639

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 17586382.

Anti-austerity activity against human PSN1 cells assessed as cell killing in nutrient deprived medium

Source:: ChEMBL

Assay data:4 Active, 2 Activity ≤ 1 µM, 5 Tested

AID:: 1758638

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 17586373.

Anti-austerity activity against human MIA PaCa-2 cells assessed as cell killing in nutrient deprived medium

Source:: ChEMBL

Assay data:4 Active, 1 Activity ≤ 1 µM, 5 Tested

AID:: 1758637

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 17586364.

Anti-austerity activity against human PANC-1 cells assessed as cell killing in nutrient deprived medium

Source:: ChEMBL

Assay data:5 Active, 4 Activity ≤ 1 µM, 5 Tested

AID:: 1758636

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 16518955.

Inhibition of recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli using p-nitrophenyl phosphate as substrate incubated for 30 mins

Source:: ChEMBL

Protein Target:: Tyrosine-protein phosphatase non-receptor type 1

Assay data:19 Active, 19 Tested

AID:: 1651895

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 13014686.

Inhibition of recombinant human PTP1B assessed as hydrolysis of p-nitrophenyl phosphate

Source:: ChEMBL

Protein Target:: Tyrosine-protein phosphatase non-receptor type 1

Assay data:3 Active, 1 Activity ≤ 1 µM, 3 Tested

AID:: 1301468

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 13014667.

Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 24 hrs by MTS assay

Source:: ChEMBL

Assay data:7 Active, 1 Activity ≤ 1 µM, 7 Tested

AID:: 1301466

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 13014658.

Cytotoxicity against human A549 cells assessed as reduction in cell viability after 24 hrs by MTS assay

Source:: ChEMBL

Assay data:4 Active, 1 Activity ≤ 1 µM, 7 Tested

AID:: 1301465

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 13014649.

Cytotoxicity against human SW480 cells assessed as reduction in cell viability after 24 hrs by MTS assay

Source:: ChEMBL

Assay data:5 Active, 7 Tested

AID:: 1301464

Summary Compounds, Active PubMed Citation

Select item 130146310.

Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 24 hrs by MTS assay

Source:: ChEMBL

Assay data:6 Active, 2 Activity ≤ 1 µM, 7 Tested

AID:: 1301463

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

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BioActivity

Active Compounds (10)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 µM (8)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Confirmatory (10)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations

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Literature Extraction (10)
BioAssays extracted from the literature

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BioAssays, Active for PubChem Compound (Select 21591148) (10)
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Concise Conserved Domain Links for Protein (Select 1730682) (1)
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