BioAssays, Active for PubChem Compound (Select 644601) - PubChem BioAssay - NCBI

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Items: 19

Select item 6243231.

Early assessment of compound solubility in aqueous buffer - Set 2

Source:: Burnham Center for Chemical Genomics

Assay data:40 Active, 91 Tested

AID:: 624323

Summary Compounds, Active PubMed Citation

Select item 6243212.

Early assessment of compound solubility in 1x PBS - Set 2

Source:: Burnham Center for Chemical Genomics

Assay data:38 Active, 89 Tested

AID:: 624321

Summary Compounds, Active PubMed Citation Related BioAssays by Depositor

Select item 5043333.

qHTS Assay for Inhibitors of BAZ2B

Source:: National Center for Advancing Translational Sciences (NCATS)

Protein Target:: bromodomain adjacent to zinc finger domain 2B

Assay data:15779 Active, 1 Activity ≤ 1 nM, 3545 Activity ≤ 1 µM, 359824 Tested

AID:: 504333

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Depositor Related BioAssays by Same Project Related BioAssays by Target

Select item 3708884.

Inhibition of human recombinant MMP8 by fluorogenic substrate assay

Source:: ChEMBL

Protein Target:: Neutrophil collagenase

Assay data:2 Active, 1 Activity ≤ 1 µM, 4 Tested

AID:: 370888

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 3708735.

Inhibition of human recombinant MMP13 by fluorogenic substrate assay

Source:: ChEMBL

Protein Target:: Collagenase 3

Assay data:4 Active, 2 Activity ≤ 1 µM, 4 Tested

AID:: 370873

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 3706296.

Inhibition of human recombinant MMP13 expressed in Escherichia coli

Source:: ChEMBL

Protein Target:: Collagenase 3

Assay data:18 Active, 2 Activity ≤ 1 µM, 31 Tested

AID:: 370629

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 3708877.

Inhibition of human recombinant ADAMTS5 at 200 uM by HxBPyne probe-based competitive activity based protein profiling assay in presence of 5 uM HxBpane competitor

Source:: ChEMBL

Protein Target:: A disintegrin and metalloproteinase with thrombospondin motifs 5

Assay data:1 Active, 3 Tested

AID:: 370887

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 3708868.

Inhibition of human recombinant MMP24 at 200 uM by HxBPyne probe-based competitive activity based protein profiling assay in presence of 5 uM HxBpane competitor

Source:: ChEMBL

Protein Target:: Matrix metalloproteinase-24

Assay data:1 Active, 3 Tested

AID:: 370886

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 3708859.

Inhibition of human recombinant MMP16 at 200 uM by HxBPyne probe-based competitive activity based protein profiling assay in presence of 5 uM HxBpane competitor

Source:: ChEMBL

Protein Target:: Matrix metalloproteinase-16

Assay data:1 Active, 3 Tested

AID:: 370885

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 37088410.

Inhibition of human recombinant MMP15 at 200 uM by HxBPyne probe-based competitive activity based protein profiling assay in presence of 5 uM HxBpane competitor

Source:: ChEMBL

Protein Target:: Matrix metalloproteinase-15

Assay data:1 Active, 3 Tested

AID:: 370884

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 37088311.

Inhibition of human recombinant MMP14 at 200 uM by HxBPyne probe-based competitive activity based protein profiling assay in presence of 5 uM HxBpane competitor

Source:: ChEMBL

Protein Target:: Matrix metalloproteinase-14

Assay data:1 Active, 3 Tested

AID:: 370883

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 37088212.

Inhibition of human recombinant MMP11 at 200 uM by HxBPyne probe-based competitive activity based protein profiling assay in presence of 5 uM HxBpane competitor

Source:: ChEMBL

Protein Target:: Stromelysin-3

Assay data:1 Active, 3 Tested

AID:: 370882

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 37087913.

Inhibition of human recombinant MMP12 at 200 uM by HxBPyne probe-based competitive activity based protein profiling assay in presence of 5 uM HxBpane competitor

Source:: ChEMBL

Protein Target:: Macrophage metalloelastase

Assay data:2 Active, 4 Tested

AID:: 370879

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 37087814.

Inhibition of human recombinant MMP10 at 200 uM by HxBPyne probe-based competitive activity based protein profiling assay in presence of 5 uM HxBpane competitor

Source:: ChEMBL

Protein Target:: Stromelysin-2

Assay data:2 Active, 4 Tested

AID:: 370878

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 37087715.

Inhibition of human recombinant MMP8 at 200 uM by HxBPyne probe-based competitive activity based protein profiling assay in presence of 5 uM HxBpane competitor

Source:: ChEMBL

Protein Target:: Neutrophil collagenase

Assay data:2 Active, 4 Tested

AID:: 370877

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 37087616.

Inhibition of human recombinant MMP3 at 200 uM by HxBPyne probe-based competitive activity based protein profiling assay in presence of 5 uM HxBpane competitor

Source:: ChEMBL

Protein Target:: Stromelysin-1

Assay data:2 Active, 4 Tested

AID:: 370876

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 37087517.

Inhibition of human recombinant MMP2 at 200 uM by HxBPyne probe-based competitive activity based protein profiling assay in presence of 5 uM HxBpane competitor

Source:: ChEMBL

Protein Target:: 72 kDa type IV collagenase

Assay data:2 Active, 4 Tested

AID:: 370875

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 73518.

Dose-response biochemical assay for inhibitors of Matrix Metalloproteinase 13 (MMP13) activity

Source:: The Scripps Research Institute Molecular Screening Center

Protein Target:: collagenase 3 preproprotein

Assay data:15 Active, 42 Tested

AID:: 735

Summary Compounds, Active PubMed Citation Related BioAssays by Depositor Related BioAssays by Same Project Related BioAssays by Target

Select item 57019.

Primary biochemical high-throughput screening assay for inhibitors of Matrix Metalloproteinase 13 (MMP13) activity

Source:: The Scripps Research Institute Molecular Screening Center

Protein Target:: collagenase 3 preproprotein

Assay data:46 Active, 64925 Tested

AID:: 570

Summary Compounds, Active PubMed Citation Related BioAssays by Depositor Related BioAssays by Same Project Related BioAssays by Target

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Target

Proteins (3)
BioAssays with protein sequences specified as targets

BioActivity

Active Compounds (19)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (1)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (4)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Confirmatory (5)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (1)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose

Assay Project (3)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (14)
BioAssays extracted from the literature
NIH MLP (5)
BioAssays deposited by the NIH Molecular Libraries Program

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BioAssays, Active for PubChem Compound (Select 644601) (19)
PubChem BioAssay
Homo sapiens SH3 and PX domains 2A (SH3PXD2A), transcript variant 6, mRNA
Homo sapiens SH3 and PX domains 2A (SH3PXD2A), transcript variant 6, mRNA
gi|2018536978|ref|NM_001394018.1|

Nucleotide
MAG: Microbacterium sp. 14-71-5, whole genome shotgun sequencing project
MAG: Microbacterium sp. 14-71-5, whole genome shotgun sequencing project
gi|1232994005|gb|NCKF00000000.1|NCK 0000

Nucleotide
Concise Conserved Domain Links for Protein (Select 767993111) (2)
Conserved Domains
Taxonomy Links for Protein (Select 4826724) (1)
Taxonomy

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